Brain Mapping and Sensory Motor Integration Laboratory, Institute of Psychiatry of Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Neuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n°2819 - Nossa Sra. de Fátima, Parnaíba, 64202-020, Brazil.
Neurol Sci. 2019 Jun;40(6):1183-1189. doi: 10.1007/s10072-019-03820-8. Epub 2019 Mar 8.
The low-frequency repetitive transcranial magnetic stimulation (rTMS) application has been associated with changes in cognitive processes embedded during time perception tasks. Although several studies have investigated the influence of neuromodulation on time perception, the effect of the 1-Hz rTMS application on the superior parietal cortex is not clearly understood. This study analyzes the effect of the low-frequency rTMS on time estimation when applied in the parietal medial longitudinal fissure. For the proposed study, 20 subjects were randomly selected for a crossover study with two conditions (sham and 1 Hz). Our findings reveal that participant underestimate 1-s time interval and overestimate 4-s and 9-s time intervals after 1-Hz rTMS (p ≤ 0.05). We conclude that the 1-Hz rTMS in the parietal medial longitudinal fissure delays short interval and speed up long time intervals. This could be due to the effect of parietal inhibition on the attentional level and working memory functions during time estimation.
低频重复经颅磁刺激（rTMS）的应用与时间感知任务中嵌入的认知过程的变化有关。尽管有几项研究调查了神经调节对时间感知的影响，但低频 rTMS 对顶叶上纵裂的影响尚不清楚。本研究分析了在顶叶内侧纵裂施加低频 rTMS 对时间估计的影响。对于拟议的研究，随机选择了 20 名受试者进行了一项具有两种条件（假刺激和 1Hz）的交叉研究。我们的研究结果表明，在 1Hz rTMS 后，参与者会低估 1 秒的时间间隔，高估 4 秒和 9 秒的时间间隔（p≤0.05）。我们得出结论，顶叶内侧纵裂的 1Hz rTMS 会延迟短时间间隔并加速长时间间隔。这可能是由于顶叶抑制对注意力水平和工作记忆功能的影响，从而影响时间估计。
