Department of Neurology, Ghaem hospital, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Center, Western University, ON, Canada; Department of Epidemiology and Biostatistics, Western University, ON, Canada.
Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Center, Western University, ON, Canada.
J Neurol Sci. 2019 Apr 15;399:209-213. doi: 10.1016/j.jns.2019.02.024. Epub 2019 Feb 14.
Stroke etiology and risk factors vary by age, sex, setting (hospital or community-based) and by region. Identifying these differences would improve our understanding of stroke etiology, diagnosis, and treatment.
The Age, Sex and Setting in the Etiology of Stroke Study (ASSESS) is a multicenter cohort study to assess differences in stroke etiology.
Data from all centers will be categorized according to age, sex, setting, stroke subtypes. Centers with extensive hospital- or community-based data regarding stroke from Argentina, Australia, Canada, India, Iran, Italy, Ghana, Nigeria, Thailand, the United Kingdom and the United States have agreed to participate so far.
The primary outcome includes differences in stroke etiology in study centers. The secondary outcomes include stroke incidence, risk factors, preventive strategies, and short- and long-term outcomes.
ASSESS will enable comparisons of data from different regions to determine the age and sex distribution of the most common causes of stroke in each setting. This will help clinicians to tailor the assessment and treatment of stroke patients on the basis of their specific local characteristics. It will also empower stroke epidemiologists to design preventive measures by targeting the specific characteristics of each population.
中风的病因和危险因素因年龄、性别、环境（医院或社区）和地区而异。了解这些差异将有助于我们更好地理解中风的病因、诊断和治疗。
中风病因、年龄和环境研究（ASSESS）是一项多中心队列研究，旨在评估中风病因的差异。
目前已有来自阿根廷、澳大利亚、加拿大、印度、伊朗、意大利、加纳、尼日利亚、泰国、英国和美国的多个中心同意参与此项研究，这些中心将根据年龄、性别、环境和中风亚型对数据进行分类。
主要结局包括研究中心中风病因的差异。次要结局包括中风发病率、危险因素、预防策略以及短期和长期结局。
ASSESS 将使来自不同地区的数据能够进行比较，以确定每个环境中最常见中风病因的年龄和性别分布。这将有助于临床医生根据患者的具体当地特征来调整中风患者的评估和治疗。它还将使中风流行病学家能够通过针对每个人群的特定特征来设计预防措施。
