Division of Respiratory Medicine, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
J Pediatr. 2019 May;208:279-281. doi: 10.1016/j.jpeds.2018.12.069. Epub 2019 Mar 8.
The evolution of pulmonary arteriovenous malformations (PAVMs) over time in children with hereditary hemorrhagic telangiectasia (HHT) is not well-defined. Herein we demonstrate that, although new PAVMs did not evolve in children with HHT, existing PAVMs exhibit quantitative growth over time highlighting the need for ongoing follow-up throughout childhood.
遗传性出血性毛细血管扩张症(HHT)患儿肺动静脉畸形(PAVMs)随时间的演变尚不清楚。在此,我们证明,尽管 HHT 患儿没有新的 PAVMs 出现,但现有的 PAVMs 随时间表现出定量生长,突出了在整个儿童期进行持续随访的必要性。