Section of Vascular Surgery, Department of Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Mich.
Section of Vascular Surgery, Department of Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Mich.
J Vasc Surg Venous Lymphat Disord. 2019 May;7(3):452-462. doi: 10.1016/j.jvsv.2018.12.012. Epub 2019 Mar 8.
Deep venous thrombosis (DVT) in the pediatric population is rare, occurring in about 10 to 14 out of 10,000 pediatric admissions annually, but with serious consequences such as pulmonary embolism and/or post-thrombotic syndrome. There is a dearth of surgical literature regarding this entity, its pathophysiology, its treatment and its long-term sequelae.
An extensive search of available surgical and medical literature in Medline, PubMed was obtained by searching terms synonymous with pediatric DVT. Case reports and opinion articles were excluded. Ongoing clinical trials were culled from clinicaltrial.gov by searching for pediatric DVT studies. Institutional guidelines, where available, were included in this summary.
We provide a clinically relevant summary with the aims of improving prevention, early identification and treatment of pediatric DVT.
Although rare and frequently with subtle presentations, pediatric DVT can be serious. Early identification and treatment can be instrumental in limiting sequelae and in improving outcomes for these patients.
儿科人群中的深静脉血栓（DVT）很少见，每年每 10000 名儿科住院患者中约有 10 至 14 例，但会导致严重后果，如肺栓塞和/或血栓后综合征。关于该病症的发病机制、治疗方法及其长期后果，外科文献十分匮乏。
通过在 Medline、PubMed 中搜索与儿科 DVT 同义的术语，获取了可用的外科和医学文献的广泛搜索。排除病例报告和观点文章。通过在 clinicaltrial.gov 上搜索儿科 DVT 研究，筛选出正在进行的临床试验。如有机构指南，也将其纳入本综述。
我们提供了一个具有临床相关性的总结，旨在提高对儿科 DVT 的预防、早期识别和治疗。
尽管儿科 DVT 较为罕见且常表现隐匿，但可能很严重。早期识别和治疗对于限制这些患者的后遗症和改善预后至关重要。
