Key Lab of Bioelectrochemistry & Environmental Analysis of Gansu Province, College of Chemistry & Chemical Engineering , Northwest Normal University , Lanzhou 730070 , P. R. China.
Tianjin Key Laboratory of Molecular Optoelectronic, Department of Chemistry , Tianjin University , Tianjin , 300072 , P. R. China.
Anal Chem. 2019 Apr 2;91(7):4331-4336. doi: 10.1021/acs.analchem.8b03924. Epub 2019 Mar 14.
In this work, a novel and effective ratio fluorescent porphyrin metal-organic framework (MOF) probe by encapsulating UiO-66(OH) into the porphyrin MOF (PCN-224) was prepared, showing the excellent fluorescence performance in detecting Cu. In this probe, the signal from the green-emission UiO-66(OH) encapsulated in PCN-224 was deemed as an effective reference, thus affording an effective built-in correction in complex environmental effects. The red-emission PCN-224 contained the active site for detecting Cu. At the same time, Cu can selectively quench the fluorescence intensity of PCN-224. The ratiometric probe therefore gave an effective and reliable Cu determination platform with an LOD value as low as 0.068 nM. This LOD result was better than the Cu concentration limitation in drinking water regulated by World Health Organization (WHO) and reported by some other methods. This provides a simple new sensor for rapidly detecting copper ions, which can be further expanded in various environmental and biological analysis tasks.
在这项工作中，通过将 UiO-66(OH)封装到卟啉 MOF（PCN-224）中，制备了一种新颖有效的比率荧光卟啉金属-有机骨架（MOF）探针，在检测 Cu 方面表现出优异的荧光性能。在该探针中，封装在 PCN-224 中的绿色发射 UiO-66(OH)的信号被视为有效的参考，从而在复杂的环境影响下提供了有效的内置校正。红色发射的 PCN-224 包含用于检测 Cu 的活性位点。同时，Cu 可以选择性地猝灭 PCN-224 的荧光强度。因此，比率探针提供了一个有效可靠的 Cu 测定平台，LOD 值低至 0.068 nM。这个 LOD 结果优于世界卫生组织（WHO）规定的饮用水中铜浓度限值，也优于一些其他方法的报道。这为快速检测铜离子提供了一种简单的新传感器，可进一步扩展到各种环境和生物分析任务中。
