• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项用于评估阻塞性冠状动脉疾病可能性的基因表达检测

A Gene Expression Test to Assess the Likelihood of Obstructive Coronary Artery Disease

作者信息

Mason Jeff, Frey Nina

PMID:30855773
Abstract

Coronary artery disease is the most common form of cardiovascular disease in Canada. A new blood test, Corus CAD, combines age, sex, and gene expression in an algorithm to determine the likelihood a person has obstructive coronary artery disease. Corus CAD is intended for use in patients with suspected undiagnosed obstructive coronary artery disease. There is interest in assessing Corus CAD in patient groups such as women with obstructive coronary artery disease who often have atypical symptoms and may not always be appropriately referred for follow-up testing. Studies have evaluated whether Corus CAD may help clinicians rule out coronary artery disease in some patients when used as a complement to patient history, risk factors, symptoms, physical examination, and other diagnostic tests.

摘要

冠状动脉疾病是加拿大最常见的心血管疾病形式。一种新的血液检测方法Corus CAD,通过一种算法综合年龄、性别和基因表达情况,以确定一个人患阻塞性冠状动脉疾病的可能性。Corus CAD旨在用于疑似未确诊阻塞性冠状动脉疾病的患者。人们有兴趣在诸如患有阻塞性冠状动脉疾病的女性等患者群体中评估Corus CAD,这些女性通常有非典型症状,可能并不总是能被适当地转诊进行后续检测。研究已经评估了Corus CAD作为患者病史、风险因素、症状、体格检查及其他诊断测试的补充手段时,是否有助于临床医生在某些患者中排除冠状动脉疾病。

相似文献

1
A Gene Expression Test to Assess the Likelihood of Obstructive Coronary Artery Disease一项用于评估阻塞性冠状动脉疾病可能性的基因表达检测
2
Use of the Corus® CAD Gene Expression Test for Assessment of Obstructive Coronary Artery Disease Likelihood in Symptomatic Non-Diabetic Patients.使用Corus® CAD基因表达检测评估有症状非糖尿病患者发生阻塞性冠状动脉疾病的可能性。
PLoS Curr. 2013 Aug 26;5:ecurrents.eogt.0f04f6081905998fa92b99593478aeab. doi: 10.1371/currents.eogt.0f04f6081905998fa92b99593478aeab.
3
The Clinical Utility of a Precision Medicine Blood Test Incorporating Age, Sex, and Gene Expression for Evaluating Women with Stable Symptoms Suggestive of Obstructive Coronary Artery Disease: Analysis from the PRESET Registry.纳入年龄、性别和基因表达的精准医学血液检测评估有稳定阻塞性冠状动脉疾病症状女性患者的临床效用:来自 PRESET 登记研究的分析。
J Womens Health (Larchmt). 2019 May;28(5):728-735. doi: 10.1089/jwh.2018.7203. Epub 2019 Jan 17.
4
A gender-specific blood-based gene expression score for assessing obstructive coronary artery disease in nondiabetic patients: results of the Personalized Risk Evaluation and Diagnosis in the Coronary Tree (PREDICT) trial.一种基于性别特异性血液的基因表达评分,用于评估非糖尿病患者的阻塞性冠状动脉疾病:Personalized Risk Evaluation and Diagnosis in the Coronary Tree (PREDICT) 试验的结果。
Am Heart J. 2012 Sep;164(3):320-6. doi: 10.1016/j.ahj.2012.05.012. Epub 2012 Jul 24.
5
Association of Age With the Diagnostic Value of Coronary Artery Calcium Score for Ruling Out Coronary Stenosis in Symptomatic Patients.年龄与冠状动脉钙评分对有症状患者排除冠状动脉狭窄的诊断价值的相关性。
JAMA Cardiol. 2022 Jan 1;7(1):36-44. doi: 10.1001/jamacardio.2021.4406.
6
Danish study of Non-Invasive testing in Coronary Artery Disease 2 (Dan-NICAD 2): Study design for a controlled study of diagnostic accuracy.丹麦非侵入性冠状动脉疾病检测 2 号研究(Dan-NICAD 2):一项针对诊断准确性的对照研究的研究设计。
Am Heart J. 2019 Sep;215:114-128. doi: 10.1016/j.ahj.2019.03.016. Epub 2019 May 1.
7
Utility of a Precision Medicine Test in Elderly Adults with Symptoms Suggestive of Coronary Artery Disease.老年有疑似冠心病症状患者中精准医疗检测的效用。
J Am Geriatr Soc. 2018 Feb;66(2):309-315. doi: 10.1111/jgs.15215. Epub 2017 Dec 6.
8
Rheumatoid arthritis complicates noninvasive whole blood gene expression testing for coronary artery disease.类风湿性关节炎使冠状动脉疾病的非侵入性全血基因表达检测变得复杂。
Am Heart J. 2017 Oct;192:13-18. doi: 10.1016/j.ahj.2017.06.013. Epub 2017 Jul 2.
9
Clinical likelihood models calibrated against observed obstructive coronary artery disease on computed tomography angiography.根据计算机断层扫描血管造影术观察到的阻塞性冠状动脉疾病校准的临床可能性模型。
Eur Heart J Cardiovasc Imaging. 2025 Apr 30;26(5):802-813. doi: 10.1093/ehjci/jeaf049.
10
Danish study of Non-Invasive testing in Coronary Artery Disease (Dan-NICAD): study protocol for a randomised controlled trial.丹麦冠状动脉疾病无创检测研究(Dan-NICAD):一项随机对照试验的研究方案
Trials. 2016 May 26;17(1):262. doi: 10.1186/s13063-016-1388-z.