Mason Jeff, Frey Nina
Coronary artery disease is the most common form of cardiovascular disease in Canada. A new blood test, Corus CAD, combines age, sex, and gene expression in an algorithm to determine the likelihood a person has obstructive coronary artery disease. Corus CAD is intended for use in patients with suspected undiagnosed obstructive coronary artery disease. There is interest in assessing Corus CAD in patient groups such as women with obstructive coronary artery disease who often have atypical symptoms and may not always be appropriately referred for follow-up testing. Studies have evaluated whether Corus CAD may help clinicians rule out coronary artery disease in some patients when used as a complement to patient history, risk factors, symptoms, physical examination, and other diagnostic tests.
冠状动脉疾病是加拿大最常见的心血管疾病形式。一种新的血液检测方法Corus CAD,通过一种算法综合年龄、性别和基因表达情况,以确定一个人患阻塞性冠状动脉疾病的可能性。Corus CAD旨在用于疑似未确诊阻塞性冠状动脉疾病的患者。人们有兴趣在诸如患有阻塞性冠状动脉疾病的女性等患者群体中评估Corus CAD,这些女性通常有非典型症状,可能并不总是能被适当地转诊进行后续检测。研究已经评估了Corus CAD作为患者病史、风险因素、症状、体格检查及其他诊断测试的补充手段时,是否有助于临床医生在某些患者中排除冠状动脉疾病。