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[自体瓣膜感染性心内膜炎的手术指征及结果。基于104例手术治疗病例]

[Indications and results of surgery in native valve infectious endocarditis. Apropos of 104 surgically-treated cases].

作者信息

Bru P, Manuel C, Iacono C, Vaillant A, Malméjac C, Houël J

出版信息

Arch Mal Coeur Vaiss. 1986 Jan;79(1):47-51.

PMID:3085609
Abstract

From 1972 to 1984, 104 cases of aortic valve infectious endocarditis were treated surgically. The average age of the patients was 40 years and the majority were men (69/104). Forty patients had no previous cardiac disease; 44 patients had documented valvular heart disease, which was unlikely in the remaining 20 patients. There were 16 mitral valve, 55 aortic valve, 1 tricuspid, 30 mitro-aortic, 1 mitro-tricuspid and 1 mitro-aorto-tricuspid valve infections. Aerococcus viridans was isolated in only 4 out of 71 positive cultures: the prevalence of the infecting organisms was otherwise normal (30 staphylococcus, 30 streptococcus, 7 rare organisms). Forty one patients were operated because of haemodynamic deterioration, 13 for resistant infection and 13 for an association of both indications; 37 patients were operated for embolism or threatening vegetations. Eight patients were in functional Class I, 26 in Class II, 52 in Class III and 17 in Class IV. The patients were divided into 4 groups according to the degree of surgical emergency (26 extremely urgent, 26 semi urgent, 32 controlled endocarditis and 20 chronic endocarditis). The actuarial survival rate was 70% at 5 years. Poor prognostic factors were the presence of previous valve disease, the isolation of a staphylococcus and an aortic valve localisation. The degree of emergency and the precise surgical indication did not seem to be important. Most patients at long term were in functional Classes I or II. There was no preferential indication for bioprosthetic or mechanical valve replacement in endocarditis.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1972年至1984年期间,104例主动脉瓣感染性心内膜炎患者接受了手术治疗。患者的平均年龄为40岁,大多数为男性(69/104)。40例患者既往无心脏病史;44例患者有明确的瓣膜性心脏病,其余20例患者不太可能有。有16例二尖瓣、55例主动脉瓣、1例三尖瓣、30例二尖瓣-主动脉瓣、1例二尖瓣-三尖瓣和1例二尖瓣-主动脉瓣-三尖瓣感染。在71份阳性培养物中,仅4份分离出绿色气球菌:感染病原体的流行情况在其他方面正常(30例葡萄球菌、30例链球菌、7例罕见病原体)。41例患者因血流动力学恶化接受手术,13例因耐药感染接受手术,13例因两种指征同时存在接受手术;37例患者因栓塞或有威胁的赘生物接受手术。8例患者心功能为I级,26例为II级,52例为III级,17例为IV级。根据手术紧急程度将患者分为4组(26例极紧急、26例半紧急、32例控制型心内膜炎和20例慢性心内膜炎)。5年精算生存率为70%。预后不良因素包括既往瓣膜病、葡萄球菌分离以及主动脉瓣受累。紧急程度和确切的手术指征似乎并不重要。大多数长期患者心功能为I级或II级。在心内膜炎中,生物瓣膜或机械瓣膜置换没有优先指征。(摘要截选至250词)

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