Department of Orthopaedics, Wuxi the Ninth People's Hospital Affiliated to Soochow University, No. 999 Liangxi Road, Wuxi 214062, Jiangsu, China.
Department of Orthopaedics, Wuxi the Ninth People's Hospital Affiliated to Soochow University, No. 999 Liangxi Road, Wuxi 214062, Jiangsu, China.
Orthop Traumatol Surg Res. 2019 May;105(3):535-539. doi: 10.1016/j.otsr.2019.01.007. Epub 2019 Mar 8.
At present, it is still a challenge for repairing a wide range of bone defect caused by various reasons. We aimed to investigate the effect of induced membrane technique in the treatment of infectious bone defect.
The clinical data of twenty-one patients with infectious bone defect that received induced membrane technique treatment from January 2008 to August 2017 were collected for this study. The complications were recorded, and the bone defect healing and the recovery of joint function were evaluated by Paley method. The adjacent joint activities were also evaluated.
One month after the first stage of surgery, one case had wound dehiscence, and others healed well without infection. Six cases had induced membrane injury during the second stage of surgery, and 4 of them received induced membrane wrapping reconstruction. At the last follow-up, bone defect healing was excellent, the joint function was restored (the rate of excellent and good was 90.5%). The joint range of motion recovered well and the rate of excellent and good was 81.0%.
Induction membrane technique in the treatment of infectious bone defect has advantages of simple operation, rapid healing of bone defects, and low recurrence rate of infection.
目前，修复各种原因引起的大范围骨缺损仍然是一个挑战。我们旨在研究诱导膜技术在治疗感染性骨缺损中的作用。
本研究收集了 2008 年 1 月至 2017 年 8 月期间采用诱导膜技术治疗的 21 例感染性骨缺损患者的临床资料。记录并发症，并采用 Paley 法评估骨缺损愈合和关节功能恢复情况，评估相邻关节活动情况。
一期手术后 1 个月，1 例出现切口裂开，其余切口均愈合良好，无感染。二期手术中有 6 例出现诱导膜损伤，其中 4 例接受了诱导膜包裹重建。末次随访时，骨缺损愈合良好，关节功能恢复（优良率为 90.5%）。关节活动度恢复良好，优良率为 81.0%。
诱导膜技术治疗感染性骨缺损具有操作简单、骨缺损愈合迅速、感染复发率低等优点。
