Pozo Gustavo, Pérez-Escutia Maria Angeles, Ruíz Ana, Ferrando Alejandro, Milanés Ana, Cabello Eduardo, Díaz Raul, Prado Alejandro, Pérez-Regadera Jose Fermin
Department of Medical Physics, Hospital Universitario 12 de Octubre, Madrid, Spain.
Department of Radiation Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Rep Pract Oncol Radiother. 2019 Mar-Apr;24(2):239-244. doi: 10.1016/j.rpor.2019.02.003. Epub 2019 Feb 26.
Owing to predictable or unpredictable causes, interruptions may arise during therapy. On average, the extension of fractionated radiotherapy treatments is prone to be delayed by several weeks and interruptions can come up extending overall treatment time (OTT). Clonogenic cells of aggressive tumors might benefit from this situation, modifying local control (LC). Preserving treatment quality in radiotherapy is an essential issue for the treatment outcome, and our institution is increasingly concerned about this line of work. Establishing some objective criteria to schedule patients that have suffered interruptions along their treatments is of capital importance and not a trivial issue. Publications strongly encourage departments to minimize the effect of lag periods during treatments. Therefore, in July 2017, our facility implemented the so called 'Protocol to Manage Interruptions in Radiotherapy', based on a scoring system for patient categorization that considers not only histology but also associated comorbidity and sequence of the therapy.
由于可预测或不可预测的原因,治疗过程中可能会出现中断。平均而言,分次放射治疗的疗程延长容易延迟数周,中断会导致总治疗时间(OTT)延长。侵袭性肿瘤的克隆源性细胞可能会从这种情况中获益,从而改变局部控制(LC)。在放射治疗中保持治疗质量是治疗结果的一个重要问题,我们机构越来越关注这方面的工作。建立一些客观标准来安排治疗过程中出现中断的患者至关重要,并非小事。出版物强烈鼓励各科室尽量减少治疗期间延迟期的影响。因此,2017年7月,我们的机构实施了所谓的“放射治疗中断管理方案”,该方案基于一种用于患者分类的评分系统,该系统不仅考虑组织学,还考虑相关合并症和治疗顺序。