T2*-加权磁共振成像在骨巨细胞瘤中的表现：影像学-病理学相关性研究。

T2*-weighted MR imaging findings of giant cell tumors of bone: radiological-pathological correlation.

机构信息

Department of Radiology, Kizawa Memorial Hospital, 590 Shimokobi, Kobi-cho, Minokamo City, Gifu, 505-8503, Japan.

Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.

出版信息

Jpn J Radiol. 2019 Jun;37(6):473-480. doi: 10.1007/s11604-019-00829-z. Epub 2019 Mar 11.

DOI:10.1007/s11604-019-00829-z

PMID:30859458

Abstract

PURPOSE

To assess the correlation between T2*-weighted MR imaging and pathological findings of giant cell tumors (GCT) of bone.

METHODS

Of the 33 patients with histopathologically proven GCT of bone, 12 were examined using 1.5-T MR imaging, including T2*-weighted imaging, and were included in this study. The imaging and pathological findings of GCTs were compared between GCTs with and without hypointensity on T2*-weighted images (T2* hypointensity).

RESULTS

T2* hypointensity was observed in 6 out of 12 (50%) GCTs. Septal formation (83% vs. 17%; p < 0.05) and cystic formation (67% vs. 0%; p < 0.05) on T2-weighted images was significantly more frequent in the GCTs with T2* hypointensity compared with those without T2* hypointensity. Among the six GCTs with T2* hypointensity, a large amount of hemosiderin deposition was pathologically observed in five (83%) cases, whereas small amounts of hemosiderin deposition was seen in one (17%) case. In contrast, among the six GCTs without T2* hypointensity, a small amount of hemosiderin deposition was pathologically observed in all six (100%).

CONCLUSION

Half of the GCTs showed T2* hypointensity, which is characteristic of hemosiderin deposition; whereas, the other half did not show T2* hypointensity due to a small amount of hemosiderin deposition.

摘要

目的

评估 T2*-加权磁共振成像与骨巨细胞瘤（GCT）的病理表现之间的相关性。

方法

在 33 例经组织病理学证实的骨 GCT 患者中，有 12 例接受了 1.5-T MR 成像检查，包括 T2*-加权成像，并纳入本研究。比较了 T2*-加权图像（T2*低信号）上有无低信号的 GCT 的影像学和病理学表现。

结果

在 12 例 GCT 中，有 6 例（50%）出现 T2低信号。T2 加权图像上出现分隔形成（83%比 17%；p<0.05）和囊性形成（67%比 0%；p<0.05）的 GCT 在 T2低信号的 GCT 中明显比在没有 T2低信号的 GCT 中更常见。在 T2低信号的 6 例 GCT 中，有 5 例（83%）病理上观察到大量含铁血黄素沉积，1 例（17%）观察到少量含铁血黄素沉积。相比之下，在 T2*低信号的 6 例 GCT 中，所有 6 例（100%）均观察到少量含铁血黄素沉积。