Servicio de Medicina Preventiva y Salud Pública, Hospital Vital Álvarez Buylla, Mieres. Asturias., España.
Facultad de Medicina. Universidad de Oviedo.
Rev Esp Enferm Dig. 2019 May;111(5):402-404. doi: 10.17235/reed.2019.5963/2018.
Patients with inflammatory bowel disease are likely to receive immunomodulation treatment and therefore, should be properly vaccinated. Despite their proven safety, vaccines are not exempt from adverse reactions. The clinical case was a young female with ulcerative colitis under mesalazine treatment, who developed leukocytoclastic vasculitis following vaccination for pneumococci, varicella and hepatitis A. This adverse reaction after the previously mentioned vaccines is barely described in the literature and has never been reported in a patient with an underlying condition.
患有炎症性肠病的患者可能需要接受免疫调节治疗，因此应该进行适当的疫苗接种。尽管疫苗已被证实安全，但也并非完全没有不良反应。本临床病例为一名年轻女性，患有溃疡性结肠炎，正在接受美沙拉嗪治疗，在接种肺炎球菌、水痘和甲型肝炎疫苗后发生白细胞碎裂性血管炎。文献中几乎没有描述过这种在上述疫苗接种后的不良反应，在患有基础疾病的患者中也从未有过报道。
