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英国人群中第二次髋部骨折的短期风险因素。

Short-term risk factors for a second hip fracture in a UK population.

作者信息

Sheikh Hassaan Q, Hossain Fahad S, Khan Sayeed, Usman Mohammad, Kapoor Harish, Aqil Adeel

机构信息

Leeds Teaching Hospitals, Great George St, Leeds, LS1 3EX, UK.

Barnsley Hospital Trust, Gawber Rd, Barnsley, S75 2EP, UK.

出版信息

Eur J Orthop Surg Traumatol. 2019 Jul;29(5):1055-1060. doi: 10.1007/s00590-019-02412-8. Epub 2019 Mar 12.

Abstract

INTRODUCTION

A hip fracture carries significant morbidity and mortality-a second fracture of the contralateral hip carries even higher complications. Most second hip fractures occur within 48 months of the first. The aim of this study was to comprehensively analyse all identifiable variables that may increase the risk of a contralateral hip fracture within this time period.

METHODS

We retrospectively analysed 1242 consecutive patients with hip fractures presenting to our institution. All patient-related, surgery-related and inpatient variables were collected from the index admission. We then identified patients with a subsequent contralateral hip fracture in the following 2 years. Univariate and multivariate analyses were performed to identify risk factors associated with a second fracture.

RESULTS

A total of 66 patients (5.3%) had a contralateral hip fracture in the 2 years following initial hip fracture. Mean age at first presentation was 81 years, and mean time to second fracture was 305 days. Following multivariate analysis, the patients at highest risk of a second fracture were those with dementia, acute inpatient chest infection, urinary tract infection and multiple comorbidities as measured by the Charlson score. Discharge destination after initial fracture was not associated with the risk of a second fracture.

CONCLUSIONS

We have identified a number of discrete risk factors that are associated with a short- to medium-term risk of contralateral hip fracture that may be useful in screening for patients at risk and provide them with focused medical rehabilitation.

摘要

引言

髋部骨折会带来严重的发病率和死亡率——对侧髋部再次骨折会引发更高的并发症。大多数对侧髋部骨折发生在首次骨折后的48个月内。本研究的目的是全面分析在此时间段内可能增加对侧髋部骨折风险的所有可识别变量。

方法

我们回顾性分析了连续1242例在我院就诊的髋部骨折患者。从首次入院时收集所有与患者、手术及住院相关的变量。然后确定在接下来2年内发生对侧髋部骨折的患者。进行单因素和多因素分析以确定与再次骨折相关的危险因素。

结果

共有66例患者(5.3%)在首次髋部骨折后的2年内发生了对侧髋部骨折。首次就诊时的平均年龄为81岁,再次骨折的平均时间为305天。多因素分析后,再次骨折风险最高的患者是患有痴呆、急性住院期间胸部感染、尿路感染以及根据查尔森评分患有多种合并症的患者。首次骨折后的出院去向与再次骨折的风险无关。

结论

我们已经确定了一些与对侧髋部骨折短期至中期风险相关的离散危险因素,这可能有助于筛查有风险的患者,并为他们提供有针对性的医学康复治疗。

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