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本文引用的文献

1
A Comprehensive Analysis of the Causes and Predictors of 30-Day Mortality Following Hip Fracture Surgery.髋部骨折手术后30天死亡率的原因及预测因素综合分析
Clin Orthop Surg. 2017 Mar;9(1):10-18. doi: 10.4055/cios.2017.9.1.10. Epub 2017 Feb 13.
2
Impact of hip fracture on hospital care costs: a population-based study.髋部骨折对医院护理费用的影响:一项基于人群的研究。
Osteoporos Int. 2016 Feb;27(2):549-58. doi: 10.1007/s00198-015-3277-9. Epub 2015 Aug 19.
3
Increased risk of hip fractures in patients with dementia: a nationwide population-based study.痴呆症患者髋部骨折风险增加:一项基于全国人口的研究。
BMC Neurol. 2014 Sep 12;14:175. doi: 10.1186/s12883-014-0175-2.
4
Risk analysis for second hip fracture in patients after hip fracture surgery: a nationwide population-based study.髋部骨折手术后患者再次发生髋部骨折的风险分析:一项全国范围内基于人群的研究。
J Am Med Dir Assoc. 2014 Oct;15(10):725-31. doi: 10.1016/j.jamda.2014.05.010. Epub 2014 Jul 10.
5
Incidence of second hip fracture and compliant use of bisphosphonate.第二次髋部骨折的发生率和双膦酸盐的依从性使用。
Osteoporos Int. 2013 Jul;24(7):2099-104. doi: 10.1007/s00198-012-2250-0. Epub 2012 Dec 18.
6
Ten-year risk of second hip fracture. A NOREPOS study.十年内再次髋部骨折的风险。NOREPOS 研究。
Bone. 2013 Jan;52(1):493-7. doi: 10.1016/j.bone.2012.09.009. Epub 2012 Sep 18.
7
Risk of refracture associated with compliance and persistence with bisphosphonate therapy in Taiwan.台湾地区与双膦酸盐治疗依从性和持久性相关的再骨折风险。
Osteoporos Int. 2013 Feb;24(2):511-21. doi: 10.1007/s00198-012-1984-z. Epub 2012 May 16.
8
Characteristics and outcome in patients sustaining a second contralateral fracture of the hip.发生对侧髋部二次骨折患者的特征及预后
J Bone Joint Surg Br. 2012 Jan;94(1):102-6. doi: 10.1302/0301-620X.94B1.27983.
9
The risk of a second hip fracture in patients after their first hip fracture.患者首次髋部骨折后再次发生髋部骨折的风险。
Calcif Tissue Int. 2012 Jan;90(1):14-21. doi: 10.1007/s00223-011-9545-6. Epub 2011 Nov 12.
10
Risk factors for second hip fractures among elderly patients.老年患者二次髋部骨折的危险因素。
J Orthop Sci. 2010 Mar;15(2):192-7. doi: 10.1007/s00776-009-1440-x. Epub 2010 Apr 1.

英国人群中第二次髋部骨折的短期风险因素。

Short-term risk factors for a second hip fracture in a UK population.

作者信息

Sheikh Hassaan Q, Hossain Fahad S, Khan Sayeed, Usman Mohammad, Kapoor Harish, Aqil Adeel

机构信息

Leeds Teaching Hospitals, Great George St, Leeds, LS1 3EX, UK.

Barnsley Hospital Trust, Gawber Rd, Barnsley, S75 2EP, UK.

出版信息

Eur J Orthop Surg Traumatol. 2019 Jul;29(5):1055-1060. doi: 10.1007/s00590-019-02412-8. Epub 2019 Mar 12.

DOI:10.1007/s00590-019-02412-8
PMID:30864015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6570666/
Abstract

INTRODUCTION

A hip fracture carries significant morbidity and mortality-a second fracture of the contralateral hip carries even higher complications. Most second hip fractures occur within 48 months of the first. The aim of this study was to comprehensively analyse all identifiable variables that may increase the risk of a contralateral hip fracture within this time period.

METHODS

We retrospectively analysed 1242 consecutive patients with hip fractures presenting to our institution. All patient-related, surgery-related and inpatient variables were collected from the index admission. We then identified patients with a subsequent contralateral hip fracture in the following 2 years. Univariate and multivariate analyses were performed to identify risk factors associated with a second fracture.

RESULTS

A total of 66 patients (5.3%) had a contralateral hip fracture in the 2 years following initial hip fracture. Mean age at first presentation was 81 years, and mean time to second fracture was 305 days. Following multivariate analysis, the patients at highest risk of a second fracture were those with dementia, acute inpatient chest infection, urinary tract infection and multiple comorbidities as measured by the Charlson score. Discharge destination after initial fracture was not associated with the risk of a second fracture.

CONCLUSIONS

We have identified a number of discrete risk factors that are associated with a short- to medium-term risk of contralateral hip fracture that may be useful in screening for patients at risk and provide them with focused medical rehabilitation.

摘要

引言

髋部骨折会带来严重的发病率和死亡率——对侧髋部再次骨折会引发更高的并发症。大多数对侧髋部骨折发生在首次骨折后的48个月内。本研究的目的是全面分析在此时间段内可能增加对侧髋部骨折风险的所有可识别变量。

方法

我们回顾性分析了连续1242例在我院就诊的髋部骨折患者。从首次入院时收集所有与患者、手术及住院相关的变量。然后确定在接下来2年内发生对侧髋部骨折的患者。进行单因素和多因素分析以确定与再次骨折相关的危险因素。

结果

共有66例患者(5.3%)在首次髋部骨折后的2年内发生了对侧髋部骨折。首次就诊时的平均年龄为81岁,再次骨折的平均时间为305天。多因素分析后,再次骨折风险最高的患者是患有痴呆、急性住院期间胸部感染、尿路感染以及根据查尔森评分患有多种合并症的患者。首次骨折后的出院去向与再次骨折的风险无关。

结论

我们已经确定了一些与对侧髋部骨折短期至中期风险相关的离散危险因素,这可能有助于筛查有风险的患者,并为他们提供有针对性的医学康复治疗。