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精神分裂症患者中强迫症的患病率以及对阳性和阴性症状、认知及生活质量的影响

Prevalence of Obsessive-Compulsive Disorder in Patients With Schizophrenia and Outcome on Positive and Negative Symptoms, Cognition, and Quality of Life.

作者信息

Wehbé Joelle, Haddad Chadia, Obeid Sahar, Hallit Souheil, Haddad Georges

机构信息

Faculty of Sciences, Lebanese University, Fanar.

Psychiatric Hospital of the Cross, Jal Eddib.

出版信息

J Nerv Ment Dis. 2019 Apr;207(4):239-245. doi: 10.1097/NMD.0000000000000956.

Abstract

The objectives were to examine the prevalence of obsessive-compulsive disorder (OCD) in hospitalized patients with schizophrenia and to compare the clinical, cognitive, and functional characteristics of schizophrenia patients with and without OCD. This cross-sectional study, performed between May and August 2018, enrolled 308 patients (200 men and 108 women). The prevalence of OCD in patients with schizophrenia was 3.2%. An increase in patients having a mild β was significantly associated with higher social relationship score (β = 1.68) and the Memory Functioning Scale-Informant (MFS-I) version (β = 5.67). OCD did not affect the positive and negative symptoms of these patients. The prevalence of OCD in these patients was low (3.2%). Schizophrenia patients with and without OCD have comparable clinical profiles with few exceptions. The existence of OCD may affect the social relationship quality of life and the MFS-I version.

摘要

目的是研究精神分裂症住院患者中强迫症(OCD)的患病率,并比较伴有和不伴有OCD的精神分裂症患者的临床、认知和功能特征。这项横断面研究于2018年5月至8月进行,纳入了308名患者(200名男性和108名女性)。精神分裂症患者中OCD的患病率为3.2%。轻度β值升高与较高的社会关系得分(β = 1.68)和记忆功能量表-知情者版(MFS-I)显著相关(β = 5.67)。OCD不影响这些患者的阳性和阴性症状。这些患者中OCD的患病率较低(3.2%)。伴有和不伴有OCD的精神分裂症患者除少数情况外具有可比的临床特征。OCD的存在可能会影响社会关系生活质量和MFS-I版。

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