Morita K, Watanabe M, Fuwa N
Gan No Rinsho. 1986 Apr;32(4):371-8.
From 1967 through 1982, 206 patients with stage III carcinoma of the uterine cervix were treated by conformation radiotherapy. In the first half of the period (group A), external irradiation alone was used, while in the second half (group B), intracavitary irradiation with a low dose-rate was applied in combination with external irradiation. The two-year local control rate was 56.9% in group A and 81.5% in group B. With the combined use of intracavitary irradiation, the five-year actuarial survival rate was also improved from 45.5% in group A to 59.7% in group B. At the same time, the frequency of late injury of the rectum, sigmoid colon and the urinary bladder was also decreased with the use of small sources. It can be concluded that the combined application of intracavitary irradiation and external irradiation is important to improve the treatment results of stage III carcinoma of the uterine cervix.
1967年至1982年期间，206例III期子宫颈癌患者接受了适形放疗。在该时期的前半段（A组），仅采用体外照射，而后半段（B组）则采用低剂量率腔内照射联合体外照射。A组的两年局部控制率为56.9%，B组为81.5%。随着腔内照射的联合使用，五年精算生存率也从A组的45.5%提高到了B组的59.7%。同时，使用小源时，直肠、乙状结肠和膀胱的晚期损伤发生率也有所降低。可以得出结论，腔内照射与体外照射联合应用对于提高III期子宫颈癌的治疗效果很重要。
