Ampil F L
Department of Radiology, Louisiana State University, School of Medicine, Shreveport 71130.
Radiat Med. 1990 Sep-Oct;8(5):184-7.
A review of 21 women irradiated because of stage IV-A carcinoma of the cervix was undertaken to determine whether applied external beam pelvic irradiation (EBPI) and intracavitary brachytherapy (ICB) for the disease would result in improved survival but at the price of irradiation-induced fistula formation in the tumor-involved bladder or rectum. Based on the 14 evaluable patients who received megavoltage EBPI, the five-year survival rate was better when EBPI was applied with ICB than with EBPI alone, 33% versus 0%, respectively (p = 0.06). All seven cases of vesicovaginal or rectovaginal fistulas were observed in the presence of malignant tumor. Fistula formation did not occur in any of the six patients who received EBPI with ICB.
对21例因IV - A期宫颈癌接受放疗的女性进行了回顾性研究，以确定针对该疾病应用盆腔外照射（EBPI）和腔内近距离放疗（ICB）是否会提高生存率，但代价是在肿瘤累及的膀胱或直肠形成放疗诱导的瘘管。基于14例接受兆伏级EBPI的可评估患者，当EBPI与ICB联合应用时五年生存率优于单独应用EBPI，分别为33%和0%（p = 0.06）。所有7例膀胱阴道或直肠阴道瘘均在存在恶性肿瘤的情况下观察到。接受EBPI联合ICB的6例患者中均未发生瘘管形成。
