Cereceres Aragón Andrea, Rodrigo García Joaquín, Álvarez Parrilla Emilio, Rodríguez Tadeo Alejandra
Universidad Autónoma de Ciudad Juárez.
Nutr Hosp. 2019 Apr 10;36(2):470-478. doi: 10.20960/nh.2171.
Introduction: currently, the elderly population is increasing and with it, the presence of diseases. Phenolic compounds are substances that have antioxidant properties which can impact on the prevention of oxidative damage, closely related to the onset of various diseases. Most phenolic compounds are bioaccessible and bioavailable through mechanical, enzymatic and chemical routes. However, during aging these factors are modified, affecting the absorption of these compounds. Objective: to know the recent information related to the consumption of phenolic compounds and implications for health in the elderly. Methods: a search was made in different academic bases and/or search engines (EBSCOHOST, PubMed and Science Direct) about total phenol consumption in older adults. This information was analyzed and subclassified considering chronic diseases. Results: older adults have an intake of phenolic compounds ranging from 280 ± 130 to 2,771 ± 1,552 mg/day and the amount that reflects a benefit against cardiovascular diseases, metabolic syndrome and diabetes in older adults ranges from 322 ± 153 to 2,861 mg/day. Conclusion: in some cases, the consumption of polyphenols in the elderly is not enough to generate a prevention against different diseases, so increasing their quantity is recommended. There are different situations that modify bioaccessibility and bioavailability, including the deficiency of polyphenol transporters, so the amount needed is modified to carry out its action in the body. There are few studies of this type in this population, so more research is recommended.
目前,老年人口正在增加,随之而来的是疾病的出现。酚类化合物是具有抗氧化特性的物质,可影响氧化损伤的预防,而氧化损伤与多种疾病的发生密切相关。大多数酚类化合物可通过机械、酶促和化学途径实现生物可及性和生物利用性。然而,在衰老过程中,这些因素会发生改变,影响这些化合物的吸收。目的:了解与酚类化合物摄入相关的最新信息及其对老年人健康的影响。方法:在不同学术数据库和/或搜索引擎(EBSCOHOST、PubMed和ScienceDirect)中搜索有关老年人总酚摄入量的信息。根据慢性病对这些信息进行分析和分类。结果:老年人酚类化合物的摄入量为280±130至2771±1552毫克/天,对老年人心血管疾病、代谢综合征和糖尿病有预防作用的摄入量范围为322±153至2861毫克/天。结论:在某些情况下,老年人多酚的摄入量不足以预防不同疾病,因此建议增加摄入量。存在多种改变生物可及性和生物利用性的情况,包括多酚转运体缺乏,因此需要调整所需量以使其在体内发挥作用。针对该人群的此类研究较少,因此建议开展更多研究。