Hayashi Takuma, Sakakura Noriaki, Ishimura Daisuke, Kozawa Eiji, Yoshida Masahiro, Sakao Yukinori, Yamada Harumoto, Tsukushi Satoshi
Department of Orthopedic Surgery, Aichi Cancer Center Hospital, Nagoya, Aichi 464-8681, Japan.
Department of Orthopedic Surgery, Fujita Health University, Toyoake, Aichi 470-1192, Japan.
Oncol Lett. 2019 Mar;17(3):3446-3456. doi: 10.3892/ol.2019.9997. Epub 2019 Jan 31.
Postoperative complications of thoracic wall resection include respiratory complications, skin necrosis and infection. The aim of the present study was to examine postoperative complications in patients who required combined thoracic wall resection during the surgical removal of a tumor. The present study included 68 patients; there were 50 patients with lung tumors and 18 patients with musculoskeletal tumors. The clinical factors associated with complications were compared between the two groups. Preoperative and postoperative pulmonary function tests were performed to examine the residual pulmonary function in 16 patients. Thoracic cage reconstruction was performed in 46 patients. Postoperative complications occurred in 30 (44.1%) patients, and one patient died from postoperative pneumonitis. Compared with the pulmonary function preoperative test results, the postoperative results revealed a decrease in the mean vital capacity percentage and an increase in the mean forced expiratory volume within 1 sec as a percent of the forced vital capacity. In patients with lung tumors, pneumonectomy can result in an increased rate of complications following thoracic wall resection. Residual pulmonary function is affected by impaired thoracic cage expansion and removal of the lung. However, the results of the present study demonstrated that these complications can be somewhat stabilized by thoracic wall reconstruction.
胸壁切除术后的并发症包括呼吸并发症、皮肤坏死和感染。本研究的目的是检查在肿瘤手术切除过程中需要联合胸壁切除的患者的术后并发症。本研究纳入了68例患者;其中50例为肺部肿瘤患者,18例为肌肉骨骼肿瘤患者。比较了两组与并发症相关的临床因素。对16例患者进行了术前和术后肺功能测试以检查残余肺功能。46例患者进行了胸廓重建。30例(44.1%)患者发生了术后并发症,1例患者死于术后肺炎。与术前肺功能测试结果相比,术后结果显示平均肺活量百分比下降,1秒用力呼气量占用力肺活量的百分比增加。在肺部肿瘤患者中,肺切除可导致胸壁切除术后并发症发生率增加。残余肺功能受胸廓扩张受损和肺切除的影响。然而,本研究结果表明,胸廓重建可在一定程度上稳定这些并发症。