Singh Aditi, Bhagat Milind, Siddiqui Ahmad D, Thapa Simant S
Internal Medicine, St. Vincent Hospital, Worcester, USA.
Internal Medicine, Rhode Island Hospital, Providence, USA.
Cureus. 2019 Jan 2;11(1):e3813. doi: 10.7759/cureus.3813.
We present a case of peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) masquerading as a skin rash which progressively worsened over a year. After being treated for various dermatologic and infectious etiologies, he did not feel any relief and presented to our hospital. Imaging showed generalized lymphadenopathy. Later, lymph node biopsy and skin biopsy confirmed the diagnosis of CD30 + peripheral T-cell lymphoma. He was soon started on chemotherapy with cyclophosphamide, doxorubicin, etoposide, vincristine, and prednisone (CHOEP). However, because of the aggressive nature of his disease and advanced stage at presentation, he succumbed to complications and died of sepsis. This case highlights the importance of considering a rash as one of the early symptoms of an underlying life-threatening disease.
我们报告一例未另行指定的外周T细胞淋巴瘤（PTCL-NOS），该病例伪装成皮疹，在一年多的时间里逐渐加重。在针对各种皮肤病学和感染性病因进行治疗后，他并未感到任何缓解，随后前来我院就诊。影像学检查显示全身淋巴结肿大。后来，淋巴结活检和皮肤活检确诊为CD30 +外周T细胞淋巴瘤。他很快开始接受环磷酰胺、阿霉素、依托泊苷、长春新碱和泼尼松（CHOEP）化疗。然而，由于他的疾病具有侵袭性且就诊时已处于晚期，他最终因并发症死于败血症。该病例凸显了将皮疹视为潜在危及生命疾病早期症状之一的重要性。
