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展望:利用短波长桌面光源实现单次时间分辨显微镜技术

Perspective: Towards single shot time-resolved microscopy using short wavelength table-top light sources.

作者信息

Helk T, Zürch M, Spielmann C

出版信息

Struct Dyn. 2019 Feb 5;6(1):010902. doi: 10.1063/1.5082686. eCollection 2019 Jan.

Abstract

Time-resolved imaging allows revealing the interaction mechanisms in the microcosm of both inorganic and biological objects. While X-ray microscopy has proven its advantages for resolving objects beyond what can be achieved using optical microscopes, dynamic studies using full-field imaging at the nanometer scale are still in their infancy. In this perspective, we present the current state of the art techniques for full-field imaging in the extreme-ultraviolet- and soft X-ray-regime which are suitable for single exposure applications as they are paramount for studying dynamics in nanoscale systems. We evaluate the performance of currently available table-top sources, with special emphasis on applications, photon flux, and coherence. Examples for applications of single shot imaging in physics, biology, and industrial applications are discussed.

摘要

时间分辨成像能够揭示无机和生物物体微观世界中的相互作用机制。虽然X射线显微镜已证明其在解析物体方面的优势,能够超越光学显微镜所能达到的水平,但在纳米尺度下使用全场成像进行动态研究仍处于起步阶段。从这个角度来看,我们介绍了极紫外和软X射线波段全场成像的当前技术水平,这些技术适用于单次曝光应用,因为它们对于研究纳米级系统中的动力学至关重要。我们评估了当前可用桌面光源的性能,特别强调了应用、光子通量和相干性。还讨论了单次成像在物理、生物学和工业应用中的实例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62b2/6404932/a2344b79aca6/SDTYAE-000006-010902_1-g001.jpg

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