Peking University Institute of Mental Health,National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital),Key Laboratory of Mental Health,Ministry of Health (Peking University),Beijing,100191,China.
Yulin Center for Disease Control and Prevention,Shaanxi, 719000,China.
Epidemiol Infect. 2019 Jan;147:e94. doi: 10.1017/S0950268819000049.
Gender inequality has severe consequences on public health in terms of delay in diagnosis of pulmonary tuberculosis (PTB). In order to explore gender-related differences in diagnosis delay, a cross-sectional study of 10 686 patients diagnosed with PTB in Yulin from 1 January 2009 to 31 December 2014 was conducted. Diagnosis delay was categorised into 'short delay' and 'long delay' by four commonly used cut-off points of 14, 30, 60 and 90 days. Logistic regression analysis was used to analyse gender differences in diagnostic delay. Stratified analyses by smear results, age, urban/rural were performed to examine whether the effect persisted across the strata. The median delay was 31 days (interquartile range 13-65). Diagnostic delay in females at cut-off points of 14, 30, 60 and 90 days had odds ratios (OR) of 0.99 (95% CI 0.91-1.09), 1.09 (95% CI 1.01-1.18), 1.15 (95% CI 1.05-1.26) and 1.18 (95% CI 1.06-1.31), respectively, compared with males. Stratified analysis showed that females were associated with increased risk of longer delay among those aged 30-60 years, smear positive and living in the rural areas (P < 0.05). The female-to-male OR increased along with increased delay time. Further inquiry into the underlying reasons for gender differences should be urgently addressed to improve the current situation.
性别不平等对公共卫生造成了严重影响,尤其是在肺结核(PTB)的诊断延迟方面。为了探讨诊断延迟中的性别差异,对 2009 年 1 月 1 日至 2014 年 12 月 31 日在榆林市诊断为肺结核的 10686 例患者进行了一项横断面研究。将诊断延迟分为“短延迟”和“长延迟”,采用 14、30、60 和 90 天四个常用截止点。使用逻辑回归分析来分析性别诊断延迟差异。按涂片结果、年龄、城乡进行分层分析,以检查该效果是否在各层之间持续存在。中位数延迟为 31 天(四分位距 13-65)。在 14、30、60 和 90 天的截止点,女性的诊断延迟比值比(OR)分别为 0.99(95%CI 0.91-1.09)、1.09(95%CI 1.01-1.18)、1.15(95%CI 1.05-1.26)和 1.18(95%CI 1.06-1.31),与男性相比。分层分析表明,在 30-60 岁、涂片阳性和农村地区的人群中,女性与较长的延迟时间相关,风险增加(P < 0.05)。女性与男性的 OR 随着延迟时间的增加而增加。应紧急调查性别差异的根本原因,以改善现状。