Sector for Biostatistics and Data Repository, National Institutes of Health, Ministry of Health Malaysia, Shah Alam 40170, Selangor, Malaysia.
Biomedical Epidemiology Unit, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Shah Alam 40170, Selangor, Malaysia.
Int J Environ Res Public Health. 2022 May 21;19(10):6258. doi: 10.3390/ijerph19106258.
: Gender plays a significant role in health-care-seeking behavior for many diseases. Delays in seeking treatment, diagnosis, and treatment for pulmonary tuberculosis (pTB) may increase the risk of transmission in the community and lead to poorer treatment outcomes and mortality. This study explores the differences in factors associated with the total delay in treatment of male and female pTB patients in Selangor, Malaysia. : A cross-sectional study was conducted from January 2017 to December 2017. Newly diagnosed pTB patients (≥18 years) were recruited from selected government health clinics and hospitals in Selangor during the specified study period. An interviewer-administered questionnaire was used to collect information on sociodemographic characteristics, lifestyle, knowledge about pTB, stigma, distance to the nearest health facility, and chronology of pTB symptom onset, diagnosis, and treatment. The total delay was measured as the length of time between the onset of pTB symptoms to treatment initiation. Factors significantly associated with a longer total delay among men and women were identified using binary logistic regression. : A total of 732 patients (61.5% men, 38.5% women) were enrolled in the study. The median total delay was 60 days. Men who have weight loss as a symptom (AOR: 1.63, 95%CI: 1.10-2.41) and are employed (1.89, 1.15-3.11) were more likely to have a longer total delay, while those who know others who have had pTB (0.64, 0.43-0.96) were less likely to have a longer total delay. On the other hand, among women, having a stigma towards TB (0.52, 0.32-0.84) and obtaining a pTB diagnosis at the first medical consultation (0.48, 0.29-0.79) were associated with a shorter total delay. : Factors associated with the total delay in pTB treatment were different for male and female pTB patients. Increasing awareness of pTB symptoms and the importance of seeking early medical consultation and a prompt diagnosis among the general public may reduce total delay in pTB treatment.
性别在许多疾病的医疗保健寻求行为中起着重要作用。对于肺结核(pTB),延迟治疗、诊断和治疗可能会增加在社区中传播的风险,并导致治疗效果和死亡率更差。本研究探讨了马来西亚雪兰莪州男性和女性肺结核患者治疗总延迟相关因素的差异。
这是一项横断面研究,于 2017 年 1 月至 2017 年 12 月进行。在指定的研究期间,从雪兰莪州选定的政府卫生诊所和医院招募了新诊断的肺结核患者(≥18 岁)。使用访谈者管理的问卷收集社会人口统计学特征、生活方式、肺结核知识、耻辱感、到最近卫生机构的距离以及肺结核症状发作、诊断和治疗的时间顺序等信息。总延迟时间测量为肺结核症状发作至开始治疗的时间长度。使用二元逻辑回归确定与男性和女性总延迟时间较长相关的因素。
共有 732 名患者(61.5%为男性,38.5%为女性)参与了研究。中位数总延迟时间为 60 天。有体重减轻症状(AOR:1.63,95%CI:1.10-2.41)和有工作的男性(1.89,1.15-3.11)更有可能出现总延迟时间较长,而那些知道有其他人患有肺结核(0.64,0.43-0.96)的人则不太可能出现总延迟时间较长。另一方面,对于女性,对结核病的耻辱感(0.52,0.32-0.84)和在首次就诊时获得肺结核诊断(0.48,0.29-0.79)与总延迟时间较短有关。
肺结核治疗总延迟的相关因素在男性和女性肺结核患者中有所不同。提高公众对肺结核症状的认识以及对早期求医和及时诊断的重视,可能会降低肺结核治疗的总延迟时间。