Brooke Army Medical Center, Fort Sam Houston, TX, USA.
Headache. 2019 Jun;59(6):917-923. doi: 10.1111/head.13505. Epub 2019 Mar 14.
To explore the neuropsychological correlates and implications of familial hemiplegic migraines (FHMs).
FMH is a rare, autosomal dominant subtype of migraine that only occurs in 0.01% of the population. Little is known about the neuropsychological impact of FHMs; however, cognitive impairment associated with cerebellar syndrome has been identified in some cases.
A single case study involving a 24-year-old male who recently endured an atypical, prolonged FHM episode.
The patient's overall neuropsychological functioning was intact with low average semantic fluency and processing speed, and mild indications of executive dysfunction.
Baseline and serial neuropsychological testing in individuals with FHM may help identify the potential progression and course of cognitive impairment associated with this condition.
探讨家族性偏瘫性偏头痛（FMH）的神经心理学相关性及其意义。
FMH 是一种罕见的常染色体显性偏头痛亚型，仅发生在人群中的 0.01%。关于 FMH 的神经心理学影响知之甚少；然而，在某些情况下已确定与小脑综合征相关的认知障碍。
一项涉及一名最近经历了非典型、延长的 FMH 发作的 24 岁男性的单一案例研究。
患者的整体神经心理学功能正常，语义流畅性和处理速度中等偏低，执行功能轻度异常。
FMH 患者的基线和连续神经心理学测试可能有助于确定与该疾病相关的认知障碍的潜在进展和病程。
