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使用清单提高膀胱过度活动症行为疗法的效果:一项前瞻性随机对照试验。

Using a checklist to increase the effectiveness of behavioral therapy for overactive bladder: A prospective randomized controlled trial.

机构信息

Department of Urology, Medical Science University, Ankara Training and Research Hospital, Ankara, Turkey.

出版信息

Neurourol Urodyn. 2019 Apr;38(4):1152-1159. doi: 10.1002/nau.23974. Epub 2019 Mar 14.

DOI:10.1002/nau.23974
PMID:30869820
Abstract

AIM

To evaluate the benefits of a newly established checklist form of behavioral therapy for overactive bladder (OAB).

METHODS

Of a total of 180 patients suffering eight or more micturitions, two or more nocturia, seven or more urgency, or four more urinary urgency incontinence (UUI) episodes per day according to a 3-day bladder diary, 155 were randomly divided into four groups. Group I (n = 29) patients were instructed to apply only behavioral therapy as a written guideline and group II (n = 27) patients were instructed to apply behavioral therapy with a written checklist. Group III (n = 26) patients received medical treatment plus behavioral therapy without a checklist. Group IV (n = 28) patients received medical treatment with a written checklist over a 6-month period.

RESULTS

A total of 110 participants completed the study period. The demographic data and baseline voiding parameters such as frequency, urgency, nocturia, and UUI of the participants in all four groups were similar (P > 0.05 for all). At the end of the study period, the highest rates of treatment response (64.3%) and adherence (85.7%) were determined for the patients with antimuscarinic drugs plus checklist. The persistence rate of patients using antimuscarinics with the checklist was higher than that of those using antimuscarinics plus a written guideline of behavioral therapy (75.4% vs 60.2%).

CONCLUSION

The effectiveness of behavioral therapy for OAB can be improved with this newly designed checklist. In addition, the adherence and persistence rate of medical treatment may also improve with the checklist used.

摘要

目的

评估新制定的行为治疗膀胱过度活动症(OAB)检查表形式的益处。

方法

根据 3 天膀胱日记,共有 180 名每天有 8 次以上排尿、2 次以上夜尿、7 次以上尿急或 4 次以上尿急性尿失禁(UUI)发作的患者,随机分为 4 组。第 I 组(n=29)患者仅接受行为治疗作为书面指南,第 II 组(n=27)患者接受行为治疗和书面检查表。第 III 组(n=26)患者接受药物治疗加行为治疗,无检查表。第 IV 组(n=28)患者接受药物治疗和书面检查表,为期 6 个月。

结果

共有 110 名参与者完成了研究期。所有 4 组患者的人口统计学数据和基线排尿参数(如频率、尿急、夜尿和 UUI)相似(P>0.05 所有)。在研究期末,抗毒蕈碱药物加检查表的患者治疗反应率(64.3%)和依从率(85.7%)最高。使用检查表的抗毒蕈碱药物患者的持续率高于使用抗毒蕈碱药物加行为治疗书面指南的患者(75.4%比 60.2%)。

结论

新设计的检查表可提高行为治疗 OAB 的疗效。此外,使用检查表还可能提高药物治疗的依从性和持续率。

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