Stevanovic Dejan, Bozic-Antic Ivana, Stanojlovic Olivera, Vojnovic Milutinovic Danijela, Bjekic-Macut Jelica, Jancic Jasna, Macut Djuro
Clinic of Neurology and Psychiatry for Children and Youth , Belgrade , Serbia.
Clinic of Endocrinology, Diabetes and Metabolic Diseases, Faculty of Medicine, University of Belgrade , Belgrade , Serbia.
Women Health. 2019 Oct;59(9):1015-1025. doi: 10.1080/03630242.2019.1587664. Epub 2019 Mar 14.
This study aimed to analyze the measurement properties of the Health-related quality of life questionnaire for polycystic ovary syndrome (PCOSQ-50) in a sample of Serbian women with polycystic ovary syndrome (PCOS). Seventy-six women with PCOS from an endocrinology clinic and 28 healthy women participated between October 2016 and March 2017. The measure was rigorously translated and culturally adapted into Serbian. Psychometric evaluation included descriptive analysis, internal consistency (Cronbach's alpha coefficient), test-retest reliability (intraclass-correlation coefficient - ICC) and construct validity testing. Cronbach's alpha coefficient ranged from 0.67 to 0.96 for domain scales of PCOSQ-50 scores, while the ICCs for test-retest reliability for these domains ranged from 0.66 to 0.89. Women with PCOS had significantly lower scores than healthy women for hirsutism, obesity and menstrual disorders and the total PCOSQ-50 scale score (p ≤ 0.03), but not for the psychosocial and emotional, fertility, sexual function, and coping scales. These results show that the Serbian PCOSQ-50 measure is acceptable and could produce reliable and valid assessments of PCOS-related quality of life for at least four out of seven domains. Considering that validity testing is an iterative process, additional work is needed before the whole measure is used in routine clinical practice.
本研究旨在分析多囊卵巢综合征健康相关生活质量问卷（PCOSQ - 50）在塞尔维亚多囊卵巢综合征（PCOS）女性样本中的测量属性。2016年10月至2017年3月期间，来自内分泌诊所的76名PCOS女性和28名健康女性参与了研究。该测量工具经过严格翻译并在文化上进行了调整以适应塞尔维亚语。心理测量学评估包括描述性分析、内部一致性（克朗巴哈α系数）、重测信度（组内相关系数 - ICC）和结构效度测试。PCOSQ - 50得分的领域量表的克朗巴哈α系数在0.67至0.96之间，而这些领域重测信度的ICC在0.66至0.89之间。PCOS女性在多毛症、肥胖和月经紊乱以及PCOSQ - 50总量表得分方面显著低于健康女性（p≤0.03），但在心理社会和情感、生育能力、性功能及应对量表方面并非如此。这些结果表明，塞尔维亚语版PCOSQ - 50测量工具是可接受的，并且至少在七个领域中的四个领域能够对PCOS相关生活质量进行可靠且有效的评估。鉴于效度测试是一个迭代过程，在该完整测量工具用于常规临床实践之前，还需要开展更多工作。
