Urfer Silvan R, Wang Mansen, Yang Mingyin, Lund Elizabeth M, Lefebvre Sandra L
From the Department of Medicine Pathology, University of Washington, Seattle, Washington (S.R.U.); Providence Health & Services, Renton, Washington (M.W.); Banfield Pet Hospital, Vancouver, Washington (M.Y.); DataDogs, LLC, Lake Oswego, Oregon (E.M.L.); and American Veterinary Medical Association, Schaumburg, Illinois (S.L.L.).
J Am Anim Hosp Assoc. 2019 May/Jun;55(3):130-137. doi: 10.5326/JAAHA-MS-6763. Epub 2019 Mar 14.
The objective of this population-based retrospective cohort study was to identify factors associated with lifespan in pet dogs evaluated at primary care veterinary hospitals. Dogs ≥3 mo of age that visited any of 787 US hospitals at least twice from January 1, 2010, through December 31, 2012, were included. Survival curves were constructed for dogs by reproductive status, breed, body size, and purebreed (versus mixed-breed) status. Multivariate Cox proportional hazard regression was performed to identify factors associated with lifespan. There were 2,370,078 dogs included in the study, of whom 179,466 (7.6%) died during the study period. Mixed-breed dogs lived significantly longer than purebred dogs, and this difference was more pronounced as body size increased. Controlling for other factors, dogs of either sex had a greater hazard of death over the study follow-up period if sexually intact rather than gonadectomized. For dogs who lived to 2 yr of age, the hazard of death decreased with increasing frequency of dental scaling. Our findings support previous reports of the impact of body size and gonadectomy on lifespan and provide new evidence in support of ultrasonic dental scaling and mixed breeding.
这项基于人群的回顾性队列研究的目的是确定在初级保健兽医医院接受评估的宠物狗寿命的相关因素。纳入了2010年1月1日至2012年12月31日期间至少两次就诊于美国787家医院中任何一家的年龄≥3个月的狗。根据生殖状况、品种、体型和纯种（与混种）状况为狗构建生存曲线。进行多变量Cox比例风险回归以确定与寿命相关的因素。该研究共纳入2370078只狗，其中179466只（7.6%）在研究期间死亡。混种狗的寿命明显长于纯种狗，且随着体型增大这种差异更为明显。在控制其他因素的情况下，在研究随访期间，未绝育的雌雄狗比绝育的狗死亡风险更高。对于活到2岁的狗，牙齿洁治频率增加，死亡风险降低。我们的研究结果支持了先前关于体型和绝育对寿命影响的报道，并为超声牙齿洁治和混种繁殖提供了新的证据。
