Kim Suk Jung, Kim Woo Gyeong
Department of Radiology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
Am J Case Rep. 2019 Mar 15;20:340-344. doi: 10.12659/AJCR.914178.
BACKGROUND The incidence of flat epithelial atypia of the breast has been increasing owing to the increasing use of ultrasonography (US) and US-guided core needle biopsy. However, reports describing the sonographic features of flat epithelial atypia are fewer than those on its mammographic features. CASE REPORT A 47-year-old female had a regular 6 month-interval follow-up US for multiple bilateral breast masses detected on US. A new focal non-mass-like lesion measuring 2 cm in maximum diameter was noted in the 10 o'clock direction of the right breast on the follow-up US. Mammography was not performed during the follow-up period. The patient had no breast symptoms and no family history of breast cancer or other pertinent medical history. US-guided 14-gauge core needle biopsy yielded a pathological diagnosis of flat epithelial atypia without upgrade to malignancy, and this was further confirmed after complete excision of the non-mass-like lesion. CONCLUSIONS Flat epithelial atypia can present as a focal non-mass-like lesion on US, which has not been reported previously.
背景 由于超声检查(US)及US引导下的粗针活检应用增多,乳腺扁平上皮异型增生的发生率一直在上升。然而,描述扁平上皮异型增生超声特征的报告比其乳腺X线特征的报告要少。病例报告 一名47岁女性因US检查发现双侧多发乳腺肿块,每6个月定期进行随访US检查。随访US检查时,在右乳10点钟方向发现一个新的局灶性非肿块样病变,最大直径为2 cm。随访期间未进行乳腺X线摄影。患者无乳腺症状,无乳腺癌家族史或其他相关病史。US引导下14号粗针活检病理诊断为扁平上皮异型增生,未升级为恶性,在完整切除非肿块样病变后进一步得到证实。结论 扁平上皮异型增生在US上可表现为局灶性非肿块样病变,此前未见报道。