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[心肌梗死急性期行手术治疗的室间隔破裂的长期病程]

[Long-term course of septal rupture operated on during the acute phase of a myocardial infarct].

作者信息

Juliard J M, Donzeau-Gouge P, Masquet C, Piwnica A, Beaufils P

出版信息

Arch Mal Coeur Vaiss. 1986 Mar;79(3):333-7.

PMID:3087316
Abstract

Between 1970 and 1979, 28 patients (18 men and 10 women, aged 46 to 76 years, average 62 years) with acute myocardial infarction complicated by septal rupture survived surgery performed during the acute phase. In the same period 62 patients were admitted to the Cardiology Department and were operated early for septal rupture complicating myocardial infarction. The site of infarction was the anterior wall in 22 cases and the posterior wall in 6 cases; septal rupture occurred on average after 4.2 days (range 1 to 10 days); 15 patients including 13 with cardiogenic shock underwent intraaortic balloon pumping for an average of 3:7 (range 1 to 11 days) before surgery; the operation performed after an average interval of 11 days consisted in direct suture of the defect in 3 cases and a patch repair in the other 25 cases, associated in all cases with infarctectomy and LAD coronary bypass grafting in 1 case. The immediate postoperative course was simple; three patients with residual shunts were not reoperated. Five to 14 years later, in 1984, 4 patients had been lost to follow-up; 4 patients had died, 2 of cardiac causes (LVF after 1 year and an arrhythmia after 4 years). Of the 20 survivors, 2 were successfully reoperated (1 coronary bypass after 10 years and 1 false aneurysm after 5 years). Only one patient had recurrent myocardial infarction. The quality and longevity of long-term survival encourage early surgery. The factors affecting long-term survival are discussed: correction of associated valvular defects, resifual shunts, conservation of left ventricular function and evaluation of the coronary circulation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1970年至1979年间,28例急性心肌梗死并发室间隔破裂的患者(18例男性和10例女性,年龄46至76岁,平均62岁)在急性期接受了手术并存活下来。同期,62例因心肌梗死并发室间隔破裂而入住心内科并早期接受手术的患者。梗死部位在前壁22例,后壁6例;室间隔破裂平均发生在4.2天(范围1至10天)后;15例患者包括13例心源性休克患者在手术前平均3.7天(范围1至11天)接受主动脉内球囊反搏;平均间隔11天后进行的手术中,3例为缺损直接缝合,25例为补片修补,所有病例均伴有梗死切除术,1例伴有左前降支冠状动脉搭桥术。术后即刻病程简单;3例有残余分流的患者未再次手术。1984年,5至14年后,4例患者失访;4例患者死亡,2例死于心脏原因(1年后左心衰竭,4年后心律失常)。20例幸存者中,2例成功再次手术(1例10年后进行冠状动脉搭桥术,1例5年后进行假性动脉瘤修补术)。只有1例患者发生复发性心肌梗死。长期生存的质量和寿命鼓励早期手术。讨论了影响长期生存的因素:相关瓣膜缺损的纠正、残余分流、左心室功能的保留以及冠状动脉循环的评估。(摘要截短至250字)

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