Gorkem Sureyya Burcu, Doria Andrea S, Tse Shirley
Department of Diagnostic Imaging, The Hospital for Sick Children, Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
Department of Rheumatology, The Hospital for Sick Children, Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
Jpn J Radiol. 2019 May;37(5):371-379. doi: 10.1007/s11604-019-00824-4. Epub 2019 Mar 14.
Mixed connective tissue disease (MCTD) is a rare disease in children and adolescents which overlaps features of juvenile idiopathic arthritis, polymyositis/dermatomyositis, systemic lupus erythematosus, and systemic sclerosis. We have provided an image-based approach for evaluation of MCTD in children and adolescents, outlying the most frequent imaging findings. This approach would aid imagers and clinicians to consider the diagnosis of this rare entity and be able to make an accurate list of differential diagnosis for complex rheumatologic diseases such as MCTD, thus facilitating the ultimate goal of early diagnosis and optimal management of affected children.
混合性结缔组织病（MCTD）在儿童和青少年中是一种罕见疾病，它兼具幼年特发性关节炎、多发性肌炎/皮肌炎、系统性红斑狼疮和系统性硬化症的特征。我们提供了一种基于图像的方法来评估儿童和青少年的MCTD，列出了最常见的影像学表现。这种方法将有助于影像科医生和临床医生考虑对这种罕见疾病进行诊断，并能够为诸如MCTD等复杂风湿性疾病准确列出鉴别诊断清单，从而促进对患病儿童进行早期诊断和优化管理这一最终目标的实现。
