Matanhelia D M, Croghan S, Nason G J, O’Connell C, Galvin D J
Department of Urology, St Vincent’s University Hospital, Dublin 4
Department of Urology, Mater Misericordiae University Hospital, Dublin 7
Ir Med J. 2019 Feb 14;112(2):866.
Aims The aim of this study was to assess the incidence, management and outcomes of incidentally diagnosed prostate cancer following TURP. Methods A retrospective review was performed using the histopathological departments’ database of all patients who underwent a TURP across two university teaching hospitals over a ten year period. Results During the study period, a total of 826 patients underwent a TURP. 72 (10.3%) had an incidental diagnosis of CaP following TURP. 46 (63.9%) were managed expectantly while 26 (36.1%) underwent active treatment. Overall mortality was 29.2% (n=21) while cancer specific mortality was 6.9% (n=5). All these patients were in the hormonal treatment sub-group. Conclusion Our study demonstrates an expectant approach is favourable in low risk disease. Curative treatment does need to be considered for younger patients with a long life expectancy or patients with higher risk disease.
目的 本研究旨在评估经尿道前列腺电切术（TURP）后偶然诊断出的前列腺癌的发病率、治疗及预后情况。方法 利用两个大学教学医院病理科数据库，对10年间所有接受TURP手术的患者进行回顾性研究。结果 在研究期间，共有826例患者接受了TURP手术。其中72例（10.3%）在TURP术后偶然诊断为前列腺癌（CaP）。46例（63.9%）采取观察等待，26例（36.1%）接受积极治疗。总死亡率为29.2%（n = 21），癌症特异性死亡率为6.9%（n = 5）。所有这些患者均在激素治疗亚组中。结论 我们的研究表明，对于低风险疾病，观察等待是一种较好的方法。对于预期寿命长的年轻患者或高风险疾病患者，确实需要考虑进行根治性治疗。
