Roffi J, Chami F, Corbier P
C R Acad Sci III. 1986;302(12):467-70.
Neonatal male rats were castrated either at 0, 6 or 24 hrs. after birth. As adults, testosterone was delivered by subcutaneous implantation of a Silastic capsule containing this hormone. The probability to display mounting behavior in presence of an estrous female was lower when the animals were castrated at 0 hr. than at 6 or 24 hrs. or when they received a subcutaneous injection of 1 microgram of testosterone propionate, at the time of castration at 0 hr. These results suggest that in the rat, during the 6 hrs. following birth, neonatal testes influence the sensitivity of the adult central nervous system to testosterone.
新生雄性大鼠在出生后0、6或24小时进行去势。成年后，通过皮下植入含有这种激素的硅橡胶胶囊来给予睾酮。当动物在出生后0小时去势时，在有发情期雌鼠在场的情况下表现出骑跨行为的概率低于在6或24小时去势时，或者在出生后0小时去势时皮下注射1微克丙酸睾酮的情况。这些结果表明，在大鼠出生后的6小时内，新生睾丸会影响成年中枢神经系统对睾酮的敏感性。
