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妇科癌症的新型治疗方法。

New and Novel Therapies for Gynecologic Cancers.

机构信息

Division of Gynecologic Oncology, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK.

出版信息

Semin Oncol Nurs. 2019 Apr;35(2):217-219. doi: 10.1016/j.soncn.2019.02.009. Epub 2019 Mar 12.

DOI:10.1016/j.soncn.2019.02.009
PMID:30876683
Abstract

OBJECTIVE

To review recent therapies approved by the US Food and Drug Administration for the treatment of gynecologic malignancies.

DATA SOURCES

PubMed, FDA.gov, ASCO.org.

CONCLUSION

The landscape for treating gynecologic malignancies is rapidly changing. Maintenance therapy now exists for women with advanced ovarian cancer after completing chemotherapy for both newly diagnosed and platinum-sensitive recurrent ovarian cancer. Anti-angiogenic therapy has many applications in gynecologic malignancies. Immunotherapy can be used in certain situations for women with gynecologic malignancies.

IMPLICATIONS FOR NURSING PRACTICE

Biologic agents and immunotherapy have distinct side-effect profiles that nurses need to be aware of to optimize patient care and outcomes.

摘要

目的

回顾美国食品和药物管理局最近批准的用于治疗妇科恶性肿瘤的疗法。

资料来源

PubMed、FDA.gov、ASCO.org。

结论

治疗妇科恶性肿瘤的领域正在迅速变化。对于新诊断的和铂敏感的复发性卵巢癌完成化疗后,维持治疗现在可用于晚期卵巢癌患者。抗血管生成治疗在妇科恶性肿瘤中有多种应用。免疫疗法可用于某些情况下的妇科恶性肿瘤患者。

对护理实践的意义

生物制剂和免疫疗法具有不同的副作用特征,护士需要了解这些特征,以优化患者的护理和结局。

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New and Novel Therapies for Gynecologic Cancers.妇科癌症的新型治疗方法。
Semin Oncol Nurs. 2019 Apr;35(2):217-219. doi: 10.1016/j.soncn.2019.02.009. Epub 2019 Mar 12.
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Current Systemic Treatment Landscape of Advanced Gynecologic Malignancies.晚期妇科恶性肿瘤的当前全身治疗现状。
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Clin Exp Metastasis. 2018 Aug;35(5-6):521-533. doi: 10.1007/s10585-018-9889-7. Epub 2018 Jun 21.
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Advancing Drug Development in Gynecologic Malignancies.推进妇科恶性肿瘤的药物研发。
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The evolving landscape of antibody-drug conjugates in gynecologic cancers.妇科癌症中抗体药物偶联物的发展态势
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Anti-angiogenesis therapy in gynecologic malignancies.妇科恶性肿瘤的抗血管生成治疗
Oncology (Williston Park). 2015 May;29(5):350-60.
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Clinical trials in gynecologic oncology: Past, present, and future.妇科肿瘤学临床试验:过去、现在和未来。
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Improvements in progression-free and overall survival due to the use of anti-angiogenic agents in gynecologic cancers.由于在妇科癌症中使用抗血管生成药物,无进展生存期和总生存期得到改善。
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Updates in the Use of Targeted Therapies for Gynecologic Cancers.妇科癌症靶向治疗的新进展。
Am Soc Clin Oncol Educ Book. 2024 Jun;44(3):e438582. doi: 10.1200/EDBK_438582.
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Integrating antibody drug conjugates in the management of gynecologic cancers.将抗体药物偶联物整合到妇科癌症的治疗中。
Int J Gynecol Cancer. 2023 Mar 6;33(3):420-429. doi: 10.1136/ijgc-2022-003701.

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