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术前鼻牙槽塑形在双侧唇腭裂患者中的绝对和相对影响与健康新生儿的鼻生长比较。

The absolute and relative effects of presurgical nasoalveolar moulding in bilateral cleft lip and palate patients compared with nasal growth in healthy newborns.

机构信息

Department of Oral and Maxillofacial Surgery, Technische Universität München, Germany.

Department of Oral and Maxillofacial Surgery, Friedrich-Alexander-University Nürnberg-Erlangen, Germany.

出版信息

J Craniomaxillofac Surg. 2019 Jul;47(7):1083-1091. doi: 10.1016/j.jcms.2019.01.044. Epub 2019 Feb 11.

Abstract

BACKGROUND

This study investigated the efficiency of nasoalveolar moulding (NAM) in patients presenting with bilateral cleft lip and palate (BCLP). It focused explicitly on nasal outcome and therefore made comparisons with healthy age-matched infants with normal nasal development.

METHODS

Nasal impressions from 19 BCLP patients were analysed at the beginning and at the end of NAM treatment. In addition, nasal impressions from 32 healthy newborns were taken monthly for 4 months. The casts were digitalized and analysed, using defined anatomic landmarks, by two independent observers. Initial values were compared with outcome parameters at the end of NAM therapy and with the healthy cohort.

RESULTS

NAM significantly elongated the columella in BCLP patients, with an increase of 106.5% versus 14.5% in healthy newborns. Nostril height showed significant expansion from 4.2 mm to 5.6 mm on the right side, and from 4.3 mm to 6.2 mm on the left side.

CONCLUSION

NAM significantly elongated columella length and increased nostril height. The comparison with healthy newborns showed the effectiveness of early cartilage moulding. Detailed knowledge about absolute and relative early nasal growth was gained. However, despite highly effective NAM treatment in BCLP, nasal dimensions will not reach healthy proportions.

摘要

背景

本研究调查了鼻牙槽塑形(NAM)在双侧唇腭裂(BCLP)患者中的治疗效果。它特别关注鼻部结果,并与正常鼻发育的健康同龄婴儿进行了比较。

方法

在 NAM 治疗开始和结束时,对 19 例 BCLP 患者的鼻印模进行了分析。此外,对 32 例健康新生儿每月进行一次为期 4 个月的鼻印模。使用定义的解剖标志,由两名独立的观察者对印模进行数字化和分析。将初始值与 NAM 治疗结束时的结果参数以及健康组进行比较。

结果

NAM 显著延长了 BCLP 患者的鼻中隔,增加了 106.5%,而健康新生儿的增加了 14.5%。右侧鼻孔高度从 4.2 毫米增加到 5.6 毫米,左侧鼻孔高度从 4.3 毫米增加到 6.2 毫米。

结论

NAM 显著延长了鼻中隔长度,增加了鼻孔高度。与健康新生儿的比较显示了早期软骨塑形的有效性。获得了有关绝对和相对早期鼻生长的详细知识。然而,尽管 BCLP 患者的 NAM 治疗非常有效,但鼻部尺寸仍无法达到健康比例。

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