Department of Vascular and Endovascular Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Department of Vascular and Endovascular Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.
World Neurosurg. 2019 Jun;126:e1063-e1068. doi: 10.1016/j.wneu.2019.02.205. Epub 2019 Mar 13.
Carotid endarterectomy, especially eversion carotid endarterectomy (ECEA), is a standard treatment of carotid artery stenosis but continues to have deficiencies. We have described a modified ECEA technique that focuses on the quality of life (QoL), called Q-modified eversion carotid endarterectomy (QCEA). The modifications mainly include the skin incision, surgical approach, and arterial anastomosis. The purpose of the present study was to evaluate the clinical efficacy of QCEA and the QoL of patients after QCEA.
We performed a retrospective study of 109 patients were had undergone ECEA or QCEA from October 2016 to December 2017. The data from all interventions were prospectively collected in a dedicated database. The primary efficacy outcome was the composite of any stroke, myocardial infarction, or death through the 1-year follow-up period. The secondary endpoint was the QoL of patients after ECEA or QCEA on the seventh postoperative day, including incision hematoma, incision numbness, facial swelling, and scar length.
QCEA was performed in 41 patients and ECEA in 45 patients. No statistically significant differences were found in operating or clamping time between the 2 groups. The incidence of facial swelling (4.9% vs. 28.9%; P = 0.040) and incision numbness (4.9% vs. 24.4%; P = 0.011) in the QCEA group was significantly lower than that in the ECEA group. The average scar length of the QCEA group was significantly shorter than that of the ECEA group (5.1 ± 1.4 cm vs. 7.6 ± 2.1 cm; P < 0.001). No transient ischemic attack, stroke, myocardial infarction, or mortality occurred in either group during the 1-year follow-up.
Our results suggest that QCEA can reduce incision numbness, facial edema, and scar length, thereby improving the QoL of patients.
颈动脉内膜切除术,特别是外翻式颈动脉内膜切除术(ECEA),是治疗颈动脉狭窄的标准方法,但仍存在一些缺陷。我们描述了一种改良的 ECEA 技术,该技术侧重于生活质量(QoL),称为改良外翻式颈动脉内膜切除术(QCEA)。这些修改主要包括皮肤切口、手术入路和动脉吻合。本研究的目的是评估 QCEA 的临床疗效和 QCEA 后患者的生活质量。
我们对 2016 年 10 月至 2017 年 12 月期间接受 ECEA 或 QCEA 的 109 例患者进行了回顾性研究。所有干预措施的数据均前瞻性地收集在专用数据库中。主要疗效终点是 1 年随访期间任何卒中、心肌梗死或死亡的复合终点。次要终点是 ECEA 或 QCEA 术后第 7 天患者的生活质量,包括切口血肿、切口麻木、面部肿胀和疤痕长度。
41 例患者行 QCEA,45 例患者行 ECEA。两组患者的手术或夹闭时间无统计学差异。QCEA 组面部肿胀(4.9%比 28.9%;P=0.040)和切口麻木(4.9%比 24.4%;P=0.011)的发生率明显低于 ECEA 组。QCEA 组的平均疤痕长度明显短于 ECEA 组(5.1±1.4cm 比 7.6±2.1cm;P<0.001)。在 1 年的随访期间,两组均未发生短暂性脑缺血发作、卒中和心肌梗死,也没有死亡。
我们的结果表明,QCEA 可以减少切口麻木、面部水肿和疤痕长度,从而提高患者的生活质量。