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采用原位和反位技术进行全内脏转位供体肝脏移植:一例报告

Liver Transplant From a Donor With Situs Inversus Totalis Using Orthotopic and Retroversus Technique: A Case Report.

作者信息

Reimondez S, Alcaraz Á, Giordano Segade E, Agüero Ramaccioni N, Casarez Díaz G, Maraschio M A

机构信息

Hospital Privado Universitario de Córdoba, Córdoba, Argentina.

Hospital Privado Universitario de Córdoba, Córdoba, Argentina.

出版信息

Transplant Proc. 2019 Mar;51(2):585-588. doi: 10.1016/j.transproceed.2018.12.002. Epub 2018 Dec 12.

DOI:10.1016/j.transproceed.2018.12.002
PMID:30879595
Abstract

Situs inversus totalis is an infrequent genetic malformation affecting 0.01% of the population and consists of the total rotation of the organs 180 degrees, generating the so-called mirror-image reversal. For many years donors with this pathology were discouraged from organ donation. We present a case of hepatic and renal transplantation using the 2 techniques described, orthotopic and retroversus. The recipient was a 69-year-old man with end-stage liver and kidney disease due to alcoholism and diabetes, respectively, and a Model for End-Stage Liver Disease score of 32. There was no mismatch between recipient and donor. The implant started with the piggy-back technique using the retroversus technique, generating a tense portal vein anastomosis due to the superior situation of the elements of the hepatic hilum, so it was decided to undo suprahepatic anastomosis with the orthotopic technique, rotating the liver on its axis, without complications. Roux-en-Y hepaticojejunoanastomosis was carried out. The patient was discharged 15 days after surgery with normalization of renal function. Although both techniques must be taken into account, the one that fits best for a particular recipient should be used, given the particularities of size and shape of the liver graft. This can take some art and creativity from the surgical team.

摘要

全内脏反位是一种罕见的基因畸形,影响着0.01%的人口,其特征是器官整体旋转180度,形成所谓的镜像反转。多年来,患有这种病症的捐赠者一直不被鼓励进行器官捐赠。我们呈现了一例使用所述的两种技术(原位和逆向)进行肝移植和肾移植的病例。受者是一名69岁男性,分别因酗酒和糖尿病导致终末期肝病和肾病,终末期肝病模型评分32分。供受者之间无配型不合。移植手术首先采用逆向技术的背驮式技术,但由于肝门部结构位置较高,导致门静脉吻合口张力较大,因此决定采用原位技术拆除肝上吻合口,将肝脏绕其轴旋转,未出现并发症。进行了Roux-en-Y肝空肠吻合术。患者术后15天出院,肾功能恢复正常。尽管两种技术都应予以考虑,但鉴于肝移植的大小和形状特点,应选择最适合特定受者的技术。这需要手术团队具备一定的技巧和创造力。

相似文献

1
Liver Transplant From a Donor With Situs Inversus Totalis Using Orthotopic and Retroversus Technique: A Case Report.采用原位和反位技术进行全内脏转位供体肝脏移植:一例报告
Transplant Proc. 2019 Mar;51(2):585-588. doi: 10.1016/j.transproceed.2018.12.002. Epub 2018 Dec 12.
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Retroversus implantation of a liver graft: a novel approach to the deceased donor with situs inversus totalis.肝移植逆行植入:针对全内脏反位脑死亡供体的一种新方法。
Am J Transplant. 2007 Jul;7(7):1869-71. doi: 10.1111/j.1600-6143.2007.01843.x. Epub 2007 May 19.
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Retroversus Implantation of a Situs Solitus Deceased Donor Liver into a Situs Inversus Totalis Recipient.将 situs solitus 已故供体肝脏逆向植入 situs inversus totalis 受体。
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Liver Transplantation in an Adult Recipient With Situs Inversus Totalis: Case Report and Review of the Literature.全内脏反位成年受者的肝移植:病例报告及文献复习
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Classical orthotopic liver transplantation from a donor with situs inversus totalis using slight rotation of the liver graft.利用肝脏移植物轻微旋转,对全内脏转位供体进行经典原位肝移植。
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Liver transplantation in patients with situs inversus.镜像右位心患者的肝移植
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Orthotopic, but reversed implantation of the liver allograft in situs inversus totalis-a simple new approach to a difficult problem.全内脏转位患者肝脏同种异体移植的原位逆向植入——解决难题的一种简单新方法。
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Living donor liver transplantation using a right lobe graft in an adult with situs inversus.在一名内脏反位的成年人中使用右叶移植物进行活体供肝移植。
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Orthotopic liver transplantation from a donor with abdominal situs inversus.来自腹腔脏器反位供体的原位肝移植。
Transplantation. 1996 Jul 15;62(1):133-5. doi: 10.1097/00007890-199607150-00027.

引用本文的文献

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Matching the opposites: liver transplantation from a situs viscerum inversus totalis donor.匹配相反情况:来自全内脏反位供体的肝移植。
Updates Surg. 2025 Jan;77(1):77-82. doi: 10.1007/s13304-024-01968-3. Epub 2024 Nov 13.
2
Liver and pancreas transplantation in adult donor and recipients with situs inversus totalis: a case series and review of the literature.成人供体和全内脏反位受者的肝胰联合移植:病例系列及文献复习。
J Med Case Rep. 2024 Aug 29;18(1):398. doi: 10.1186/s13256-024-04720-y.
3
Situs Inversus Totalis: A Clinical Review.
完全性内脏反位:临床综述
Int J Gen Med. 2022 Mar 3;15:2437-2449. doi: 10.2147/IJGM.S295444. eCollection 2022.