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韩国出现一株携带 NDM-13 碳青霉烯酶的多重耐药临床分离大肠杆菌 ST8499 菌株。

Emergence of a multidrug-resistant clinical isolate of Escherichia coli ST8499 strain producing NDM-13 carbapenemase in the Republic of Korea.

机构信息

Infectious Diseases Team, Seoul Metropolitan Government Research Institute of Public Health and Environment, Gyeonggi-do, Republic of Korea.

Infectious Diseases Team, Seoul Metropolitan Government Research Institute of Public Health and Environment, Gyeonggi-do, Republic of Korea.

出版信息

Diagn Microbiol Infect Dis. 2019 Aug;94(4):410-412. doi: 10.1016/j.diagmicrobio.2019.02.013. Epub 2019 Feb 21.

Abstract

We described a carbapenem-resistant Escherichia coli ST8499 strain producing New Delhi metallo-β-lactamase-13 (NDM-13) from patient in Korea. The isolate exhibited multidrug resistance, but remained susceptible to colistin and tigecycline. The bla gene was located on a 130-kb self-transmissible plasmid. This is the first report of NDM-13 carbapenemase in Korea.

摘要

我们描述了一株来自韩国患者的产新德里金属β-内酰胺酶-13(NDM-13)的碳青霉烯类耐药大肠杆菌 ST8499 菌株。该分离株表现出多药耐药性,但对黏菌素和替加环素仍保持敏感。bla 基因位于一个 130kb 的可自我传递质粒上。这是韩国首次报道 NDM-13 碳青霉烯酶。

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