寄生虫和寄生虫衍生抗原在炎症性肠病炎症缓解中的治疗潜力。
Therapeutic Potential of Helminths and Helminth-Derived Antigens for Resolution of Inflammation in Inflammatory Bowel Disease.
机构信息
Department of Parasitology and Mycology, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran; Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran; Research Center for Noncommunicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran.
出版信息
Arch Med Res. 2019 Jan;50(1):58-59. doi: 10.1016/j.arcmed.2019.03.001. Epub 2019 Mar 14.
Inflammation plays a pivotal role in the pathogenesis of inflammatory bowel disease (IBD), and treatment of IBD mainly targets on inhibition of pro-inflammatory mediators. Helminth-based therapy is a novel strategy for resolution of inflammation in IBD, because helminths have great immunomodulatory properties. Helminth-based therapy may be efficacious as a vaccine for patients with IBD. This article is a highlight on the therapeutic potential of helminths in IBD.
炎症在炎症性肠病 (IBD) 的发病机制中起着关键作用，IBD 的治疗主要针对抑制促炎介质。基于寄生虫的治疗是一种治疗 IBD 炎症的新策略，因为寄生虫具有很强的免疫调节特性。寄生虫疗法可能对 IBD 患者作为疫苗有效。本文重点介绍寄生虫在 IBD 中的治疗潜力。
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