Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China.
World Neurosurg. 2019 Jun;126:601-604. doi: 10.1016/j.wneu.2019.02.225. Epub 2019 Mar 14.
Childhood absence epilepsy is a common generalized epilepsy syndrome characterized by childhood onset of frequent sporadic absence seizures. During onset, the electroencephalogram exhibits bilateral, symmetric, and synchronous discharges of approximately 3 Hz of generalized spike-and-wave complexes. Focal spikes are often found in children with focal epilepsy but are not common in absence epilepsy.
In the case patient, focal spikes were observed during active onset of absence epilepsy and at 5 years after the first hospital visit, at which time absence epilepsy was controlled and medication was withdrawn without focal seizure attack in the interim.
This case demonstrates that focal spikes associated with childhood absence epilepsy do not require specific treatment in the absence of focal seizures.
儿童失神癫痫是一种常见的全面性癫痫综合征，以儿童期频繁出现的散发性失神发作为特征。发作期间，脑电图表现为双侧、对称、同步的约 3Hz 的全面性棘慢波综合放电。局灶性棘波在局灶性癫痫儿童中很常见，但在失神性癫痫中并不常见。
在该病例患者中，在失神性癫痫发作活跃期和首次就诊后 5 年观察到局灶性棘波，在此期间，失神性癫痫得到控制，药物停用，期间无局灶性癫痫发作。
本病例表明，在无局灶性发作的情况下，与儿童失神性癫痫相关的局灶性棘波不需要特定治疗。
