Misiakos Evangelos P, Gouloumi Alina-Roxani, Schizas Dimitrios, Damaskou Vasileia, Tsapralis Dimitrios, Farrugia Frederick-Anthony, Machairas Nikolaos, Papaconstantinou Dimitrios, Tzaneti Ariadni, Machairas Anastasios
3rd Department of Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon Hospital, Athens 12462, Greece.
2nd Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Attikon Hospital, Athens 12462, Greece.
Oncol Lett. 2019 Apr;17(4):3862-3866. doi: 10.3892/ol.2019.10031. Epub 2019 Feb 12.
The present report describes the case of an 81-year-old woman who underwent an emergency explorative laparotomy due to small bowel perforation. Diffuse feculent peritonitis due to perforation of the jejunum was identified. In addition, six distinct tumors of the jejunum in close proximity to the perforation site, as well as two more lesions caudally at the ileum, were identified. A separate stenotic tumor was identified at the sigmoid colon, causing moderate dilatation of the whole intestine. An enterectomy, including the perforation site and the proximal six tumors, was performed, followed by limited enterectomies for the distal two tumors and side-to-side anastomoses of the small intestine. All resected tumors were identified at histology as metastatic from lung carcinoma. Postoperatively, the patient remained in a severe septic condition and succumbed the following day. Metastatic lesions from lung carcinoma in the small bowel wall are a rare finding predisposing to bowel perforation. When an acute condition coexists with multiple intestinal metastases, the mortality rate is high despite prompt surgical intervention.
本报告描述了一名81岁女性的病例,该患者因小肠穿孔接受了急诊剖腹探查术。术中发现空肠穿孔导致弥漫性粪性腹膜炎。此外,在穿孔部位附近发现了6个不同的空肠肿瘤,在回肠尾部还发现了另外2个病变。在乙状结肠发现了一个单独的狭窄性肿瘤,导致整个肠道中度扩张。进行了肠切除术,包括穿孔部位和近端的6个肿瘤,随后对远端的2个肿瘤进行了有限的肠切除术,并进行了小肠侧侧吻合。所有切除的肿瘤在组织学上均被鉴定为肺癌转移。术后,患者仍处于严重脓毒症状态,次日死亡。小肠壁的肺癌转移灶是一种罕见的导致肠穿孔的发现。当急性病症与多个肠道转移灶并存时,尽管及时进行手术干预,死亡率仍然很高。