Finkelstein J D, Martin J J, Harris B J
J Nutr. 1986 Jun;116(6):985-90. doi: 10.1093/jn/116.6.985.
Cystine supplementation of adequate diets resulted in significantly higher hepatic levels of betaine-homocysteine methyltransferase. Other changes occurred but were a function of the basal diet. When the latter contained 0.25% methionine + 0.5% cystine, the additional cystine caused a markedly lower hepatic cystathionine synthase activity and lower levels of both adenosylmethionine and serine. The metabolic effect of these changes may be enhanced methionine retention and diminished transsulfuration.
在充足的饮食中补充胱氨酸会导致肝脏中甜菜碱 - 高半胱氨酸甲基转移酶水平显著升高。还发生了其他变化，但这些变化取决于基础饮食。当基础饮食含有0.25%的蛋氨酸 + 0.5%的胱氨酸时，额外补充胱氨酸会导致肝脏中胱硫醚合成酶活性明显降低，同时腺苷甲硫氨酸和丝氨酸水平也降低。这些变化的代谢效应可能是增强蛋氨酸保留并减少转硫作用。
