Litt I F, Glader L
J Pediatr. 1986 Jul;109(1):150-3. doi: 10.1016/s0022-3476(86)80597-2.
We examined menstrual function in two groups of patients meeting the DSM III criteria for anorexia nervosa who differed only in their physical activity. Sixteen athletes with anorexia nervosa were compared with eight sedentary patients who had anorexia nervosa. Athletic patients with anorexia were found to have lower gonadotropin levels, a longer period of amenorrhea both before significant weight loss and after weight rehabilitation, and a higher weight at the time of resumption of menses than patients with anorexia who were sedentary. However, both groups were markedly undernourished, had amenorrhea before significant weight loss and after weight rehabilitation, and had lower gonadotropin levels than normal subjects. These data suggest that the increased physical activity often seen in patients with anorexia nervosa worsens, but does not cause, menstrual dysfunction.
我们研究了两组符合精神疾病诊断与统计手册第三版（DSM III）中神经性厌食症标准的患者的月经功能，这两组患者仅在身体活动方面存在差异。将16名患有神经性厌食症的运动员与8名久坐不动的神经性厌食症患者进行了比较。结果发现，患有神经性厌食症的运动员患者促性腺激素水平较低，在体重显著减轻之前和体重恢复之后闭经的时间更长，与久坐不动的神经性厌食症患者相比，恢复月经时的体重更高。然而，两组患者均明显营养不良，在体重显著减轻之前和体重恢复之后均出现闭经，且促性腺激素水平低于正常受试者。这些数据表明，神经性厌食症患者中常见的身体活动增加会使月经功能紊乱恶化，但并非导致月经功能紊乱的原因。
