Talbot S, Kilpatrick D, Krikler D, Oakley C M
Br Med J. 1978 Sep 9;2(6139):733-6. doi: 10.1136/bmj.2.6139.733.
Although ventricular tachycardia is a well-known complication of myocardial ischaemia and may be provoked by exercise, many patients may appreciate only the angina and be unaware of the unduly rapid heart rate that precipitates it. Exercise testing is needed to show this arrhythmia and to enable treatment to be started.Twenty-three patients were found to have chronic ischaemic heart disease complicated by ventricular tachycardia. Six patients with old myocardial infarction had ventricular tachycardia at rest which required conversion to sinus rhythm; 17 patients developed ventricular tachycardia only when they exercised. In 12 of these 17 patients coronary angiography showed disease of the anterior descending branch of the left coronary artery; other vessels were usually also affected. Although beta-adrenergic blocking drugs increased exercise tolerance, ventricular tachycardia still occurred when the heart rate on exercise reached a level similar to that before treatment. In five patients coronary artery bypass surgery was performed because of angina and exercise-induced ventricular tachycardia. Exercise tolerance was increased in all three patients who underwent exercise tests after operation, and in two of these patients, both of whom were known to have patent grafts, ventricular tachycardia was abolished.If part of the beneficial effect of coronary bypass surgery is preventing life-threatening ventricular arrhythmias it is essential to detect these, and ambulatory monitoring and stress testing have a complementary role.
虽然室性心动过速是心肌缺血的一种常见并发症,且可能由运动诱发,但许多患者可能仅感觉到心绞痛,而未意识到引发心绞痛的心率过快。需要通过运动试验来显示这种心律失常并开始治疗。发现23例患者患有慢性缺血性心脏病并伴有室性心动过速。6例陈旧性心肌梗死患者静息时出现室性心动过速,需要转为窦性心律;17例患者仅在运动时出现室性心动过速。在这17例患者中的12例,冠状动脉造影显示左冠状动脉前降支病变;其他血管通常也受到影响。尽管β-肾上腺素能阻滞剂提高了运动耐量,但当运动时心率达到治疗前相似水平时,仍会发生室性心动过速。5例患者因心绞痛和运动诱发的室性心动过速接受了冠状动脉搭桥手术。术后接受运动试验的所有3例患者运动耐量均增加,其中2例已知移植血管通畅的患者室性心动过速消失。如果冠状动脉搭桥手术的部分有益作用是预防危及生命的室性心律失常,那么检测这些心律失常至关重要,动态监测和负荷试验具有互补作用。