Rijken James, Schachenmayr Hilmar, Crowe Scott, Kairn Tanya, Trapp Jamie
GenesisCare, Flinders Private Hospital, Bedford Park, SA, Australia.
Queensland University of Technology, Brisbane, QLD, Australia.
J Appl Clin Med Phys. 2019 Apr;20(4):99-105. doi: 10.1002/acm2.12567. Epub 2019 Mar 18.
Beam matching occurs on all linacs to some degree and when two are more are matched to each other, patients are able to be transferred between machines. Quality assurance of plans can also be performed "distributively" on any of the matched linacs. The degree to which machines are matched and how this translates to like delivery of plans has been the focus of a number of studies. This concept has not yet been explored for stereotactic techniques which require a higher degree of accuracy. This study proposes beam matching criteria which allows for the distributive delivery and quality assurance of stereotactic body radiotherapy (SBRT) plans.
Two clinically relevant and complex volumetric modulated arc therapy (VMAT) SBRT spine and lung plans were chosen as benchmarking cases. These were delivered on nine previously beam matched linacs with quality assurance performed through ArcCheck and film exposure in the sagittal plane. Measured doses were compared to their treatment planning system predictions through gamma analysis at a range of criteria.
Despite differences in beam match parameters and variations in small fields, all nine linacs produced accurate deliveries with a tight deviation in the population sample. Pass rates were well above suggested tolerances at the recommended gamma criterion. Film was able to detect dose errors to a greater degree than ArcCheck.
Distributive quality assurance and delivery of stereotactic ablative radiotherapy treatments amongst beam matched linacs is certainly feasible provided the linacs are matched to a strict protocol like that suggested in this study and regular quality assurance is performed on the matched fleet. Distributive quality assurance and delivery of SBRT provides the possibility of efficiency gains for physicists as well as treatment staff.
所有直线加速器在某种程度上都会进行射束匹配,当两台或更多台直线加速器相互匹配时,患者就能在不同机器之间转移。计划的质量保证也可以在任何一台匹配的直线加速器上“分布式”进行。机器的匹配程度以及这如何转化为类似的计划交付,一直是多项研究的重点。对于需要更高精度的立体定向技术,这一概念尚未得到探索。本研究提出了射束匹配标准,以实现立体定向体部放射治疗(SBRT)计划的分布式交付和质量保证。
选择两个临床相关且复杂的容积调强弧形治疗(VMAT)SBRT脊柱和肺部计划作为基准案例。这些计划在九台先前已进行射束匹配的直线加速器上进行交付,并通过ArcCheck和矢状面的胶片曝光进行质量保证。通过在一系列标准下的伽马分析,将测量剂量与其治疗计划系统预测值进行比较。
尽管射束匹配参数存在差异且小射野存在变化,但所有九台直线加速器都实现了精确交付,总体样本偏差很小。在推荐的伽马标准下,通过率远高于建议的公差。胶片比ArcCheck能更有效地检测剂量误差。
只要直线加速器按照本研究建议的严格方案进行匹配,并对匹配的机群定期进行质量保证,在射束匹配的直线加速器之间进行立体定向消融放疗治疗的分布式质量保证和交付肯定是可行的。SBRT的分布式质量保证和交付为物理师以及治疗人员提供了提高效率的可能性。