Service de Médecine Intensive-Réanimation, Hôpital de Bicêtre, Hôpitaux Universitaires Paris-Sud.
Université Paris-Sud, Faculté de Médecine Paris-Sud, Inserm UMR S_999, Le Kremlin-Bicêtre, France.
Curr Opin Crit Care. 2019 Jun;25(3):273-279. doi: 10.1097/MCC.0000000000000608.
Transpulmonary thermodilution (TPTD) devices invasively measure not only cardiac output but also several other haemodynamic variables estimating cardiac preload, cardiac preload, systolic function, the lung oedema and systolic function, the lung oedema and the pulmonary permeability. In light of the recent literature, we describe how different indices are measured, emphasize their clinical interest and list potential limits and side-effects of the technique.
Estimation of cardiac output measurement with TPTD is now well established, at least when compared with the pulmonary artery catheter. The advantage of calibrating the pulse contour analysis, as it is allowed by TPTD indices, is clearly established over uncalibrated devices. The greatest advantage of TPTD is to measure extravascular lung water and pulmonary permeability, which may be useful to diagnose acute respiratory distress syndrome and manage fluid therapy in various critical diseases. It also allows a rapid detection of left ventricular systolic failure. The information it provides must be considered complementary to that provided by echocardiography.
TPTD provides several indices that may help in making decisions during the therapeutic management of haemodynamically unstable patients. It should be used for the most critically ill patients, whose management requires a reliable, precise and holistic view of the cardiopulmonary condition.
经肺温度稀释(TPTD)设备不仅可侵入性测量心输出量,还可测量其他几个血流动力学变量,用于评估前负荷、心脏收缩功能、肺水肿和肺通透性。根据最近的文献,我们描述了如何测量不同的指数,强调了它们的临床意义,并列出了该技术的潜在局限性和副作用。
TPTD 测量心输出量的方法现在已经得到很好的确立,至少与肺动脉导管相比是这样。通过 TPTD 指数校准脉搏轮廓分析的优势明显优于未校准设备。TPTD 的最大优势在于测量血管外肺水和肺通透性,这可能有助于诊断急性呼吸窘迫综合征,并在各种危重疾病中管理液体治疗。它还可以快速检测左心室收缩功能衰竭。它提供的信息应被视为与超声心动图提供的信息互补。
TPTD 提供了几个指数,可能有助于对血流动力学不稳定的患者进行治疗管理决策。它应该用于病情最危重的患者,这些患者的治疗需要对心肺状况进行可靠、精确和全面的评估。