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运动相关脑震荡:评估、治疗及未来方向

Sport-Related Concussion: Evaluation, Treatment, and Future Directions.

作者信息

McKeithan Lydia, Hibshman Natalie, Yengo-Kahn Aaron M, Solomon Gary S, Zuckerman Scott L

机构信息

Vanderbilt Sports Concussion Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

出版信息

Med Sci (Basel). 2019 Mar 15;7(3):44. doi: 10.3390/medsci7030044.

Abstract

Sport-related concussion (SRC) is a highly prevalent injury predominantly affecting millions of youth through high school athletes every year. In recent years, SRC has received a significant amount of attention due to potential for long-term neurologic sequelae. However, the acute symptoms and possibility of prolonged recovery account for the vast majority of morbidity from SRC. Modifying factors have been identified and may allow for improved prediction of a protracted course. Potential novel modifying factors may include genetic determinants of recovery, as well as radiographic biomarkers, which represent burgeoning subfields in SRC research. Helmet design and understanding the biomechanical stressors on the brain that lead to concussion also represent active areas of research. This narrative review provides a general synopsis of SRC, including relevant definitions, current treatment paradigms, and modifying factors for recovery, in addition to novel areas of research and future directions for SRC research.

摘要

与运动相关的脑震荡(SRC)是一种高度普遍的损伤,每年主要影响着数百万高中生运动员。近年来,由于存在长期神经后遗症的可能性,SRC受到了大量关注。然而,急性症状和恢复时间延长的可能性占SRC发病的绝大部分。已确定了一些调节因素,这些因素可能有助于更好地预测病程延长的情况。潜在的新型调节因素可能包括恢复的遗传决定因素以及影像学生物标志物,它们代表了SRC研究中新兴的子领域。头盔设计以及了解导致脑震荡的大脑生物力学应激因素也是活跃的研究领域。本叙述性综述提供了SRC的概述,包括相关定义、当前治疗模式以及恢复的调节因素,此外还介绍了SRC研究的新领域和未来方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b08/6473667/feedacdadad2/medsci-07-00044-g001.jpg

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