Abdullah Alhelali, Alrabiah A, Habib Sayed S, Aljathlany Y, Aljasser A, Bukhari M, Al-Ammar A Y
1 Department of Otolaryngology, King Saud University Medical City, Riyadh, Saudi Arabia.
2 Department of Clinical Physiology, King Saud University Medical City, Riyadh, Saudi Arabia.
Ear Nose Throat J. 2019 Feb;98(2):98-101. doi: 10.1177/0145561318823309. Epub 2019 Feb 5.
The diagnosis of subglottic stenosis (SGS) is usually made by clinical assessment and definitively by a direct endoscopic examination. This study aimed to evaluate different spirometric values in relation to anatomical grading and severity of subglottic stenosis cases of upper airway obstruction. Cases of SGS that underwent dilatational procedures endoscopically at the otolaryngology department of the King Saud University Medical City, Riyadh, Saudi Arabia, from June 2015 to October 2017 were collected. Pulmonary function test (PFT) pre- and postoperative parameters and the grades of subglottic stenosis were extracted. We compared different spirometric values to the severity of SGS and compared the pre- and postoperative results for each patient. There were 19 cases with a valid PFT study within 7 days preoperatively in addition to a documented intraoperative grading according to the Myer-Cotton grading system; 7 (36.8%) were grade 1, 8 (42.1%) were grade 2, and 4 (21.1%) were grade 3. The actual preoperative ratio of forced expiratory volume (FEV) in 1 second to peak expiratory flow (PEF) for all 19 patients ranged from 7.34 to 21.40 mL/L/min. We found a significant improvement in all spirometric parameters postdilatation including PEF ( P < .001), FEV ( P < .001), FEV/PEF ( P = .001), forced expiratory flow (FEF) from 25%, 50%, and 75% of vital capacity, respectively, FEF ( P < .001), FEF ( P = .001), FEF ( P = .048), and maximum mid-expiratory flow ( P = .002). We did not find any correlation between the severity of stenosis and spirometric values. This study revealed that spirometry is a useful marker in following up patients with subglottic stenosis and is also a good indicator to determine postairway surgery outcomes. However, these markers do not correlate with anatomical grading and the severity of subglottic stenosis.
声门下狭窄(SGS)的诊断通常通过临床评估做出,最终诊断则依靠直接内镜检查。本研究旨在评估与上气道梗阻性声门下狭窄病例的解剖分级和严重程度相关的不同肺量计值。收集了2015年6月至2017年10月期间在沙特阿拉伯利雅得国王沙特大学医学城耳鼻喉科接受内镜扩张手术的SGS病例。提取了术前和术后的肺功能测试(PFT)参数以及声门下狭窄的分级。我们将不同的肺量计值与SGS的严重程度进行比较,并比较了每位患者术前和术后的结果。除了根据迈耶 - 科顿分级系统记录的术中分级外,术前7天内有19例患者进行了有效的PFT研究;7例(36.8%)为1级,8例(42.1%)为2级,4例(21.1%)为3级。所有19例患者术前1秒用力呼气量(FEV)与呼气峰值流量(PEF)的实际比值范围为7.34至21.40 mL/L/min。我们发现扩张术后所有肺量计参数均有显著改善,包括PEF(P <.001)、FEV(P <.001)、FEV/PEF(P =.001)、分别来自肺活量25%、50%和75%的用力呼气流量(FEF)、FEF(P <.001)、FEF(P =.001)、FEF(P =.048)以及最大呼气中期流量(P =.002)。我们未发现狭窄严重程度与肺量计值之间存在任何相关性。本研究表明,肺量测定法是随访声门下狭窄患者的有用指标,也是确定气道手术后结果的良好指标。然而,这些指标与声门下狭窄的解剖分级和严重程度无关。