Nampijja Margaret, Natamba Barnabas, Mpango Richard, Kinyanda Eugene
1 Scientist, MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
2 Senior Scientist, MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Trop Doct. 2019 Jul;49(3):170-177. doi: 10.1177/0049475519837107. Epub 2019 Mar 18.
Major depressive disorder (MDD) is a major global health challenge and postnatal women may be at an increased risk for this disorder. Very few studies have tested this hypothesis in sub-Saharan Africa (SSA), so it is uncertain whether risk factors implicated elsewhere in the world are relevant in SSA. We explored prevalence and risk factors for MDD and depressive symptomatology among postnatal mothers in Kampala. Three hundred postnatal mothers at Nsambya Hospital were assessed for MDD using the DSM IV-based MINI; prevalence and risk factors were determined using frequencies and regressions, respectively. Four women (1.33%) had MDD; however, 94 (31%) had 'sub-threshold' or depressive symptomatology, with which partner violence is particularly associated. MDD is rare among postnatal women in a paying hospital in Kampala; however, the high prevalence of depressive symptomatology suggests susceptibility to MDD. Longitudinal studies should investigate this hypothesis and the susceptibility due to partner violence should guide appropriate interventions.
重度抑郁症（MDD）是一项重大的全球健康挑战，产后女性患这种疾病的风险可能会增加。在撒哈拉以南非洲（SSA），很少有研究验证这一假设，因此尚不确定世界其他地区涉及的风险因素在SSA是否相关。我们探讨了坎帕拉产后母亲中MDD和抑郁症状的患病率及风险因素。使用基于《精神疾病诊断与统计手册》第四版（DSM-IV）的MINI对Nsambya医院的300名产后母亲进行了MDD评估；分别使用频率和回归分析来确定患病率和风险因素。4名女性（1.33%）患有MDD；然而，94名（31%）有“亚阈值”或抑郁症状，伴侣暴力与这些症状尤其相关。在坎帕拉一家收费医院的产后女性中，MDD很少见；然而，抑郁症状的高患病率表明她们易患MDD。纵向研究应调查这一假设，且伴侣暴力导致的易感性应指导采取适当的干预措施。
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