Electroceramic Department, Instituto de Cerámica y Vidrio, CSIC, Kelsen 5, 28049 Madrid, Spain; NanoBioMatters Bactiblock, NanoBioMatters Industries S.L., Louis Pasteur 11, 46980 Paterna, Valencia, Spain.
Electroceramic Department, Instituto de Cerámica y Vidrio, CSIC, Kelsen 5, 28049 Madrid, Spain.
Mater Sci Eng C Mater Biol Appl. 2019 Jun;99:575-581. doi: 10.1016/j.msec.2019.02.004. Epub 2019 Feb 2.
This article reports the excellent antimicrobial response of nanoparticulate ZnO against multidrug-resistant organisms (MDROs). We demonstrate that the enhanced antimicrobial activity against MDROs depends on the crystalline defects of ZnO. Hence, this work provides insights on the ZnO-microorganism interactions, and we pose combined physico-chemical action mechanisms against resistant bacteria.
这篇文章报道了纳米氧化锌颗粒对多药耐药菌（MDROs）的优异抗菌反应。我们证明了对 MDROs 的增强抗菌活性取决于 ZnO 的晶体缺陷。因此，这项工作提供了关于 ZnO-微生物相互作用的见解，我们提出了针对耐药菌的联合物理化学作用机制。
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