Morikawa Kazuhiko, Igarashi Takao, Misumi Shigeki, Fukuda Taiki, Ojiri Hiroya, Matsudaira Hideki, Shiba Hiroaki, Sato Shun
Department of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Radiol Case Rep. 2019 Mar 6;14(5):595-601. doi: 10.1016/j.radcr.2019.02.022. eCollection 2019 May.
Metastatic neuroendocrine tumors of the liver typically appear as solid, hypervascular masses on imaging. Pseudocysts mimicking simple cysts are extremely rare. A 42-year-old Japanese woman was referred with a single pulmonary mass in the left lower lobe. No metastatic lesion was detected and no occupying lesion in the liver was observed. The lung tumor was diagnosed as an atypical carcinoid. Postoperative investigation revealed new hepatic simple cysts in the liver, which increased in size over time and changed into hemorrhagic cysts. Fluorodeoxyglucose positron emission tomography and somatostatin receptor scintigraphy using In-octreotide demonstrated no accumulation in the liver. Our patient did not have symptoms consistent with carcinoid syndrome. The patient underwent partial resection of the cystic lesions of the liver. Gross examination of the tumors demonstrated thin-wall cavitated lesions with hemorrhage which were metastases from the atypical carcinoid of the lung. When a growing cystic lesion with intracystic hemorrhage is found in the liver of a patient with a history of carcinoid tumors, pseudocysts caused by degeneration of a carcinoid metastasis should be considered as a differential diagnosis.
肝脏转移性神经内分泌肿瘤在影像学上通常表现为实性、高血管性肿块。模仿单纯囊肿的假性囊肿极为罕见。一名42岁的日本女性因左肺下叶单发肺部肿块前来就诊。未检测到转移性病变,肝脏也未观察到占位性病变。肺部肿瘤被诊断为非典型类癌。术后检查发现肝脏出现新的单纯囊肿,囊肿大小随时间增加并转变为出血性囊肿。氟脱氧葡萄糖正电子发射断层扫描和使用铟-奥曲肽的生长抑素受体闪烁扫描显示肝脏无积聚。我们的患者没有类癌综合征相关症状。患者接受了肝脏囊性病变的部分切除术。肿瘤大体检查显示为薄壁空洞性病变伴出血,这些病变是肺部非典型类癌的转移灶。当在有类癌肿瘤病史的患者肝脏中发现一个不断增大且伴有囊内出血的囊性病变时,应考虑类癌转移灶退变引起的假性囊肿作为鉴别诊断。