Kawamura J, Hida S, Yoshida O, Fujita T, Torizuka K
Gan To Kagaku Ryoho. 1986 Apr;13(4 Pt 2):1710-6.
A frontal tomographic whole-body Ga-67-citrate scan was performed on 67 patients with renal cell carcinoma to clarify the characteristics of gallium uptake by the kidney in relation to the tumor stage and grade, clinical laboratory data and prognosis. Positive gallium uptake by the kidney in 32 patients correlated well with the clinicopathologically higher stage and grade of the tumor and with abnormal values in prognostic indexes in the blood such as erythrocyte sedimentation rate, CRP alpha 2 globulin, ferritin and copper. Gallium accumulation in pulmonary metastatic lesions was found in 13 of 21 patients and all cases with positive uptake by the pulmonary metastatic lesions belonged to the gallium-positive group in the kidney. Kaplan-Meier estimation of survival rate clearly demonstrated bad prognosis in this group. Since the sensitivity of the Ga-67 scan is low but the specificity is high, positive gallium uptake is indicative of an ominous clinical course and shorter survival in patients with renal cell carcinoma.
对67例肾细胞癌患者进行了额叶断层全身镓-67柠檬酸盐扫描，以明确肾脏镓摄取与肿瘤分期、分级、临床实验室数据及预后的关系。32例患者肾脏镓摄取阳性与肿瘤临床病理分期和分级较高以及血液中红细胞沉降率、C反应蛋白、α2球蛋白、铁蛋白和铜等预后指标异常值密切相关。21例患者中有13例发现肺转移灶有镓积聚，所有肺转移灶摄取阳性的病例均属于肾脏镓摄取阳性组。Kaplan-Meier生存率估计清楚地表明该组预后不良。由于镓-67扫描的敏感性低但特异性高，肾脏镓摄取阳性表明肾细胞癌患者临床病程凶险且生存期较短。
