Levens Sara M, Sagui-Henson Sara J, Padro Meagan, Martin Laura E, Trucco Elisa M, Cooperman Nina A, Baldwin Austin S, Kassianos Angelos P, Mdege Noreen D
University of North Carolina at Charlotte, Department of Psychological Science, Charlotte, NC, United States.
Osher Center for Integrative Medicine, University of California, San Francisco, San Fransisco, CA, United States.
JMIR Res Protoc. 2019 Mar 20;8(3):e12265. doi: 10.2196/12265.
Unhealthy behaviors (eg, poor food choices) contribute to obesity and numerous negative health outcomes, including multiple types of cancer and cardiovascular and metabolic diseases. To promote healthy food choice, diet interventions should build on the dual-system model to target the regulation and reward mechanisms that guide eating behavior. Episodic future thinking (EFT) has been shown to strengthen regulation mechanisms by reducing unhealthy food choice and temporal discounting (TD), a process of placing greater value on smaller immediate rewards over larger future rewards. However, these interventions do not target the reward mechanisms that could support healthy eating and strengthen the impact of EFT-anchored programs. Increasing positive affect (PosA) related to healthy food choices may target reward mechanisms by enhancing the rewarding effects of healthy eating. An intervention that increases self-regulation regarding unhealthy foods and the reward value of healthy foods will likely have a greater impact on eating behavior compared with interventions focused on either process alone.
This study aimed to introduce a protocol that tests the independent and interactive effects of EFT and PosA on TD, food choice, and food demand in overweight and obese adults.
This protocol describes a factorial, randomized, controlled pilot study that employs a 2 (affective imagery: positive, neutral) by 2 (EFT: yes, no) design in which participants are randomized to 1 of 4 guided imagery intervention arms. In total, 156 eligible participants will complete 2 lab visits separated by 5 days. At visit 1, participants complete surveys; listen to the audio guided imagery intervention; and complete TD, food demand, and food choice tasks. At visit 2, participants complete TD, food demand, and food choice tasks and surveys. Participants complete a daily food frequency questionnaire between visits 1 and 2. Analyses will compare primary outcome measures at baseline, postintervention, and at follow-up across treatment arms.
Funding notification was received on April 27, 2017, and the protocol was approved by the institutional review board on October 6, 2017. Feasibility testing of the protocol was conducted from February 21, 2018, to April 18, 2018, among the first 32 participants. As no major protocol changes were required at the end of the feasibility phase, these 32 participants were included in the target sample of 156 participants. Recruitment, therefore, continued immediately after the feasibility phase. When this manuscript was submitted, 84 participants had completed the protocol.
Our research goal is to develop novel, theory-based interventions to promote and improve healthy decision-making and behaviors. The findings will advance decision-making research and have the potential to generate new neuroscience and psychological research to further understand these mechanisms and their interactions.
ISRCTN Registry ISRCTN11704675; http://www.isrctn.com/ISRCTN11704675 (Archived by WebCite at http://www.webcitation.org/760ouOoKG).
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/12265.
不健康行为(如不良的食物选择)会导致肥胖以及众多负面健康后果,包括多种类型的癌症、心血管疾病和代谢性疾病。为了促进健康的食物选择,饮食干预应基于双系统模型,以针对指导饮食行为的调节和奖励机制。情景未来思维(EFT)已被证明可通过减少不健康食物选择和时间折扣(TD)来加强调节机制,时间折扣是一种更看重较小即时奖励而非较大未来奖励的过程。然而,这些干预措施并未针对能够支持健康饮食并增强以EFT为基础的项目效果的奖励机制。增加与健康食物选择相关的积极情感(PosA)可能通过增强健康饮食的奖励效果来针对奖励机制。与仅专注于其中一个过程的干预措施相比,一种能增强对不健康食物的自我调节以及健康食物的奖励价值的干预措施可能会对饮食行为产生更大影响。
本研究旨在介绍一种方案,该方案测试EFT和PosA对超重和肥胖成年人的TD、食物选择和食物需求的独立及交互作用。
本方案描述了一项析因、随机、对照的试点研究,采用2(情感意象:积极、中性)×2(EFT:是、否)设计,参与者被随机分配到4个引导意象干预组中的一组。总共156名符合条件的参与者将在相隔5天的时间内完成2次实验室访视。在第1次访视时,参与者完成调查问卷;听取音频引导意象干预;并完成TD、食物需求和食物选择任务。在第2次访视时,参与者完成TD、食物需求和食物选择任务及调查问卷。参与者在第1次和第2次访视之间完成每日食物频率问卷。分析将比较各治疗组在基线、干预后和随访时的主要结局指标。
2017年4月27日收到资金通知,该方案于2017年10月6日获得机构审查委员会批准。2018年2月21日至2018年4月18日对前32名参与者进行了该方案的可行性测试。由于在可行性阶段结束时无需对方案进行重大更改,这32名参与者被纳入156名参与者的目标样本。因此,在可行性阶段结束后立即继续招募。在提交本手稿时,已有84名参与者完成了该方案。
我们的研究目标是开发基于理论的新型干预措施,以促进和改善健康决策及行为。这些发现将推动决策研究,并有可能产生新的神经科学和心理学研究,以进一步了解这些机制及其相互作用。
ISRCTN注册库ISRCTN11704675;http://www.isrctn.com/ISRCTN11704675(由WebCite存档于http://www.webcitation.org/760ouOoKG)。
国际注册报告识别码(IRRID):DERR1-10.2196/12265。